F545-0154 Screening compound: 3-(5-methyl-1,2,4-oxadiazol-3-yl)-N-[4-(trifluoromethyl)phenyl]benzamide

F545-0154 Screening compound: 3-(5-methyl-1,2,4-oxadiazol-3-yl)-N-[4-(trifluoromethyl)phenyl]benzamide
F545-0154 Screening compound: 3-(5-methyl-1,2,4-oxadiazol-3-yl)-N-[4-(trifluoromethyl)phenyl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F545-0154
3-(5-methyl-1,2,4-oxadiazol-3-yl)-N-[4-(trifluoromethyl)phenyl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F545-0154

Molecular Formula

C17H12F3N3O2 (C17 H12 F3 N3 O2)

Compound Name

3-(5-methyl-1,2,4-oxadiazol-3-yl)-N-[4-(trifluoromethyl)phenyl]benzamide

IUPAC name

3-(5-methyl-124-oxadiazol-3-yl)-N-[4-(trifluoromethyl)phenyl]benzamide

SMILES

Cc1nc(-c2cccc(C(Nc3ccc(C(F)(F)F)cc3)=O)c2)no1

InChI

InChI=1S/C17H12F3N3O2/c1-10-21-15(23-25-10)11-3-2-4-12(9-11)16(24)22-14-7-5-13(6-8-14)17(18,19)20/h2-9H,1H3,(H,22,24)

InChI Key

QTJNLOLOMGHRBL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14958574

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

347.3

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.284

Distribution Coefficient, logD

4.284

Water Solubility, LogSw

-4.49

Polar Surface Area

54.235

Acid Dissociation Constant (pKa)

11.41

Base Dissociation Constant (pKb)

-4.86

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.80

F545-0154 in Drug Discovery

Included in Screening Libraries

Glucocorticoid receptors Library (4806 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F545-0154 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F545-0154?
Check Price and Availability of F545-0154, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F545-0154 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F545-0154
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F545-0154
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F545-0154 available by request