F545-2218 Screening compound: N-(2-methyl-5-{3-[3-(piperidine-1-carbonyl)phenyl]-1,2,4-oxadiazol-5-yl}phenyl)furan-2-carboxamide

F545-2218 Screening compound: N-(2-methyl-5-{3-[3-(piperidine-1-carbonyl)phenyl]-1,2,4-oxadiazol-5-yl}phenyl)furan-2-carboxamide
F545-2218 Screening compound: N-(2-methyl-5-{3-[3-(piperidine-1-carbonyl)phenyl]-1,2,4-oxadiazol-5-yl}phenyl)furan-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F545-2218
N-(2-methyl-5-{3-[3-(piperidine-1-carbonyl)phenyl]-1,2,4-oxadiazol-5-yl}phenyl)furan-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F545-2218

Molecular Formula

C26H24N4O4 (C26 H24 N4 O4)

Compound Name

N-(2-methyl-5-{3-[3-(piperidine-1-carbonyl)phenyl]-1,2,4-oxadiazol-5-yl}phenyl)furan-2-carboxamide

IUPAC name

N-(2-methyl-5-{3-[3-(piperidine-1-carbonyl)phenyl]-124-oxadiazol-5-yl}phenyl)furan-2-carboxamide

SMILES

Cc(ccc(-c1nc(-c2cccc(C(N3CCCCC3)=O)c2)no1)c1)c1NC(c1ccco1)=O

InChI

InChI=1S/C26H24N4O4/c1-17-10-11-19(16-21(17)27-24(31)22-9-6-14-33-22)25-28-23(29-34-25)18-7-5-8-20(15-18)26(32)30-12-3-2-4-13-30/h5-11,14-16H,2-4,12-13H2,1H3,(H,27,31)

InChI Key

VSZGXXZZAGNOGM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14958643

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

456.5

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.403

Distribution Coefficient, logD

4.403

Water Solubility, LogSw

-4.26

Polar Surface Area

79.264

Acid Dissociation Constant (pKa)

11.99

Base Dissociation Constant (pKb)

-0.68

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.10

F545-2218 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F545-2218 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F545-2218?
Check Price and Availability of F545-2218, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F545-2218 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F545-2218
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F545-2218
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F545-2218 available by request