F545-2273 Screening compound: 1-(3-{5-[(1E)-2-(4-methoxyphenyl)ethenyl]-1,2,4-oxadiazol-3-yl}benzoyl)piperidine

F545-2273 Screening compound: 1-(3-{5-[(1E)-2-(4-methoxyphenyl)ethenyl]-1,2,4-oxadiazol-3-yl}benzoyl)piperidine
F545-2273 Screening compound: 1-(3-{5-[(1E)-2-(4-methoxyphenyl)ethenyl]-1,2,4-oxadiazol-3-yl}benzoyl)piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound F545-2273
1-(3-{5-[(1E)-2-(4-methoxyphenyl)ethenyl]-1,2,4-oxadiazol-3-yl}benzoyl)piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F545-2273

Molecular Formula

C23H23N3O3 (C23 H23 N3 O3)

Compound Name

1-(3-{5-[(1E)-2-(4-methoxyphenyl)ethenyl]-1,2,4-oxadiazol-3-yl}benzoyl)piperidine

IUPAC name

1-(3-{5-[(1E)-2-(4-methoxyphenyl)ethenyl]-124-oxadiazol-3-yl}benzoyl)piperidine

SMILES

COc1ccc(/C=C/c2nc(-c3cccc(C(N4CCCCC4)=O)c3)no2)cc1

InChI

InChI=1S/C23H23N3O3/c1-28-20-11-8-17(9-12-20)10-13-21-24-22(25-29-21)18-6-5-7-19(16-18)23(27)26-14-3-2-4-15-26/h5-13,16H,2-4,14-15H2,1H3

InChI Key

ZMJMAGXJNJXFHX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27175572

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

389.45

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.822

Distribution Coefficient, logD

4.822

Water Solubility, LogSw

-4.74

Polar Surface Area

55.502

Acid Dissociation Constant (pKa)

27.87

Base Dissociation Constant (pKb)

-4.02

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.10

F545-2273 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F545-2273 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F545-2273?
Check Price and Availability of F545-2273, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F545-2273 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F545-2273
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F545-2273
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F545-2273 available by request