F545-2441 Screening compound: {3-[5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazol-3-yl]phenyl}(morpholino)methanone

F545-2441 Screening compound: {3-[5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazol-3-yl]phenyl}(morpholino)methanone
F545-2441 Screening compound: {3-[5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazol-3-yl]phenyl}(morpholino)methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound F545-2441
{3-[5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazol-3-yl]phenyl}(morpholino)methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F545-2441

Molecular Formula

C22H20N4O3 (C22 H20 N4 O3)

Compound Name

{3-[5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazol-3-yl]phenyl}(morpholino)methanone

IUPAC name

n/a

SMILES

O=C(c1cc(-c2noc(Cc3c[nH]c4c3cccc4)n2)ccc1)N1CCOCC1

InChI

InChI=1S/C22H20N4O3/c27-22(26-8-10-28-11-9-26)16-5-3-4-15(12-16)21-24-20(29-25-21)13-17-14-23-19-7-2-1-6-18(17)19/h1-7,12,14,23H,8-11,13H2

InChI Key

UAXMTQJRHYZLCL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27175614

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

388.43

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.131

Distribution Coefficient, logD

3.131

Water Solubility, LogSw

-3.26

Polar Surface Area

65.737

Acid Dissociation Constant (pKa)

18.56

Base Dissociation Constant (pKb)

-3.36

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

6.00

F545-2441 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with F545-2441 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F545-2441?
Check Price and Availability of F545-2441, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F545-2441 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F545-2441
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F545-2441
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F545-2441 available by request