F545-2468 Screening compound: 4-(3-{5-[(4-chlorophenoxy)methyl]-1,2,4-oxadiazol-3-yl}benzoyl)morpholine

F545-2468 Screening compound: 4-(3-{5-[(4-chlorophenoxy)methyl]-1,2,4-oxadiazol-3-yl}benzoyl)morpholine
F545-2468 Screening compound: 4-(3-{5-[(4-chlorophenoxy)methyl]-1,2,4-oxadiazol-3-yl}benzoyl)morpholine alternative view

Chemical Structure Depiction of ChemDiv screening compound F545-2468
4-(3-{5-[(4-chlorophenoxy)methyl]-1,2,4-oxadiazol-3-yl}benzoyl)morpholine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F545-2468

Molecular Formula

C20H18ClN3O4 (C20 H18 ClN3 O4)

Compound Name

4-(3-{5-[(4-chlorophenoxy)methyl]-1,2,4-oxadiazol-3-yl}benzoyl)morpholine

IUPAC name

4-(3-{5-[(4-chlorophenoxy)methyl]-124-oxadiazol-3-yl}benzoyl)morpholine

SMILES

O=C(c1cccc(-c2noc(COc(cc3)ccc3Cl)n2)c1)N1CCOCC1

InChI

InChI=1S/C20H18ClN3O4/c21-16-4-6-17(7-5-16)27-13-18-22-19(23-28-18)14-2-1-3-15(12-14)20(25)24-8-10-26-11-9-24/h1-7,12H,8-11,13H2

InChI Key

BQQQWYBFRBEUOO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27175628

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

399.83

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.331

Distribution Coefficient, logD

3.331

Water Solubility, LogSw

-3.71

Polar Surface Area

63.366

Acid Dissociation Constant (pKa)

28.82

Base Dissociation Constant (pKb)

-5.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

F545-2468 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with F545-2468 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F545-2468?
Check Price and Availability of F545-2468, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F545-2468 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F545-2468
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F545-2468
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F545-2468 available by request