F549-1680 Screening compound: N-(3-chloro-4-methoxyphenyl)-1-[3-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)phenyl]-5-oxopyrrolidine-3-carboxamide

F549-1680 Screening compound: N-(3-chloro-4-methoxyphenyl)-1-[3-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)phenyl]-5-oxopyrrolidine-3-carboxamide
F549-1680 Screening compound: N-(3-chloro-4-methoxyphenyl)-1-[3-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)phenyl]-5-oxopyrrolidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F549-1680
N-(3-chloro-4-methoxyphenyl)-1-[3-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)phenyl]-5-oxopyrrolidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F549-1680

Molecular Formula

C24H23ClN4O4 (C24 H23 ClN4 O4)

Compound Name

N-(3-chloro-4-methoxyphenyl)-1-[3-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)phenyl]-5-oxopyrrolidine-3-carboxamide

IUPAC name

N-(3-chloro-4-methoxyphenyl)-1-[3-(5-cyclobutyl-124-oxadiazol-3-yl)phenyl]-5-oxopyrrolidine-3-carboxamide

SMILES

COc(ccc(NC(C(CC1=O)CN1c1cc(-c2noc(C3CCC3)n2)ccc1)=O)c1)c1Cl

InChI

InChI=1S/C24H23ClN4O4/c1-32-20-9-8-17(12-19(20)25)26-23(31)16-11-21(30)29(13-16)18-7-3-6-15(10-18)22-27-24(33-28-22)14-4-2-5-14/h3,6-10,12,14,16H,2,4-5,11,13H2,1H3,(H,26,31)/t16-/m0/s1

InChI Key

ZBGYJXFHAYDMFP-INIZCTEOSA-N

MDL Number (MFCD)

MFCD27175702

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

466.92

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.187

Distribution Coefficient, logD

4.180

Water Solubility, LogSw

-4.57

Polar Surface Area

79.639

Acid Dissociation Constant (pKa)

9.19

Base Dissociation Constant (pKb)

-1.17

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

33.30

F549-1680 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F549-1680 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F549-1680?
Check Price and Availability of F549-1680, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F549-1680 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F549-1680
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F549-1680
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F549-1680 available by request