F603-1252 Screening compound: N-{5-[4-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)butanamido]-2-methoxyphenyl}benzamide

F603-1252 Screening compound: N-{5-[4-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)butanamido]-2-methoxyphenyl}benzamide
F603-1252 Screening compound: N-{5-[4-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)butanamido]-2-methoxyphenyl}benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F603-1252
N-{5-[4-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)butanamido]-2-methoxyphenyl}benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F603-1252

Molecular Formula

C26H23N3O5 (C26 H23 N3 O5)

Compound Name

N-{5-[4-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)butanamido]-2-methoxyphenyl}benzamide

IUPAC name

N-{5-[4-(13-dioxo-23-dihydro-1H-isoindol-2-yl)butanamido]-2-methoxyphenyl}benzamide

SMILES

COc(ccc(NC(CCCN(C(c1c2cccc1)=O)C2=O)=O)c1)c1NC(c1ccccc1)=O

InChI

InChI=1S/C26H23N3O5/c1-34-22-14-13-18(16-21(22)28-24(31)17-8-3-2-4-9-17)27-23(30)12-7-15-29-25(32)19-10-5-6-11-20(19)26(29)33/h2-6,8-11,13-14,16H,7,12,15H2,1H3,(H,27,30)(H,28,31)

InChI Key

JFBLXEGATZFJBD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14960599

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

457.49

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.692

Distribution Coefficient, logD

2.691

Water Solubility, LogSw

-3.49

Polar Surface Area

82.643

Acid Dissociation Constant (pKa)

10.35

Base Dissociation Constant (pKb)

4.07

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.40

F603-1252 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with F603-1252 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F603-1252?
Check Price and Availability of F603-1252, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F603-1252 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F603-1252
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F603-1252
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F603-1252 available by request