F624-2769 Screening compound: 1-(4-fluorophenyl)-N-[(pyridin-2-yl)methyl]-5-(pyridin-3-yl)-1H-pyrazole-3-carboxamide

F624-2769 Screening compound: 1-(4-fluorophenyl)-N-[(pyridin-2-yl)methyl]-5-(pyridin-3-yl)-1H-pyrazole-3-carboxamide
F624-2769 Screening compound: 1-(4-fluorophenyl)-N-[(pyridin-2-yl)methyl]-5-(pyridin-3-yl)-1H-pyrazole-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F624-2769
1-(4-fluorophenyl)-N-[(pyridin-2-yl)methyl]-5-(pyridin-3-yl)-1H-pyrazole-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F624-2769

Molecular Formula

C21H16FN5O (C21 H16 FN5 O)

Compound Name

1-(4-fluorophenyl)-N-[(pyridin-2-yl)methyl]-5-(pyridin-3-yl)-1H-pyrazole-3-carboxamide

IUPAC name

1-(4-fluorophenyl)-N-[(pyridin-2-yl)methyl]-5-(pyridin-3-yl)-1H-pyrazole-3-carboxamide

SMILES

O=C(c(cc1-c2cnccc2)nn1-c(cc1)ccc1F)NCc1ncccc1

InChI

InChI=1S/C21H16FN5O/c22-16-6-8-18(9-7-16)27-20(15-4-3-10-23-13-15)12-19(26-27)21(28)25-14-17-5-1-2-11-24-17/h1-13H,14H2,(H,25,28)

InChI Key

PXQZTVVMMNQLIA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27179389

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

373.39

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.659

Distribution Coefficient, logD

2.658

Water Solubility, LogSw

-2.94

Polar Surface Area

56.536

Acid Dissociation Constant (pKa)

13.28

Base Dissociation Constant (pKb)

4.27

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.80

F624-2769 in Drug Discovery

Included in Screening Libraries

SH2 Library (10483 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Endocrine
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Mechanism of action:
  • PPI modulators
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with F624-2769 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F624-2769?
Check Price and Availability of F624-2769, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F624-2769 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F624-2769
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F624-2769
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F624-2769 available by request