F624-2803 Screening compound: N-ethyl-1-(4-fluorophenyl)-N-phenyl-5-(pyridin-3-yl)-1H-pyrazole-3-carboxamide

F624-2803 Screening compound: N-ethyl-1-(4-fluorophenyl)-N-phenyl-5-(pyridin-3-yl)-1H-pyrazole-3-carboxamide
F624-2803 Screening compound: N-ethyl-1-(4-fluorophenyl)-N-phenyl-5-(pyridin-3-yl)-1H-pyrazole-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F624-2803
N-ethyl-1-(4-fluorophenyl)-N-phenyl-5-(pyridin-3-yl)-1H-pyrazole-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F624-2803

Molecular Formula

C23H19FN4O (C23 H19 FN4 O)

Compound Name

N-ethyl-1-(4-fluorophenyl)-N-phenyl-5-(pyridin-3-yl)-1H-pyrazole-3-carboxamide

IUPAC name

N-ethyl-1-(4-fluorophenyl)-N-phenyl-5-(pyridin-3-yl)-1H-pyrazole-3-carboxamide

SMILES

CCN(C(c(cc1-c2cnccc2)nn1-c(cc1)ccc1F)=O)c1ccccc1

InChI

InChI=1S/C23H19FN4O/c1-2-27(19-8-4-3-5-9-19)23(29)21-15-22(17-7-6-14-25-16-17)28(26-21)20-12-10-18(24)11-13-20/h3-16H,2H2,1H3

InChI Key

FOLVSDWNKNVEOR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27179413

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

386.43

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.125

Distribution Coefficient, logD

4.125

Water Solubility, LogSw

-3.91

Polar Surface Area

37.927

Acid Dissociation Constant (pKa)

28.62

Base Dissociation Constant (pKb)

3.19

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.70

F624-2803 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Cardiovascular Library (22201 compounds)

Proline Kinase Library (2105 compounds)

SH2 Library (10483 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cardiovascular
  • Cancer
  • Digestive system
  • Nervous system
  • Male
  • Female
  • Endocrine
  • Cancer
  • Endocrine
  • Nervous system
  • Cardiovascular
Targets:
  • Kinases
  • Ion Channels
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with F624-2803 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F624-2803?
Check Price and Availability of F624-2803, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F624-2803 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F624-2803
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F624-2803
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F624-2803 available by request