F624-2827 Screening compound: 3-[1-(4-fluorophenyl)-3-(pyrrolidine-1-carbonyl)-1H-pyrazol-5-yl]pyridine

F624-2827 Screening compound: 3-[1-(4-fluorophenyl)-3-(pyrrolidine-1-carbonyl)-1H-pyrazol-5-yl]pyridine
F624-2827 Screening compound: 3-[1-(4-fluorophenyl)-3-(pyrrolidine-1-carbonyl)-1H-pyrazol-5-yl]pyridine alternative view

Chemical Structure Depiction of ChemDiv screening compound F624-2827
3-[1-(4-fluorophenyl)-3-(pyrrolidine-1-carbonyl)-1H-pyrazol-5-yl]pyridine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F624-2827

Molecular Formula

C19H17FN4O (C19 H17 FN4 O)

Compound Name

3-[1-(4-fluorophenyl)-3-(pyrrolidine-1-carbonyl)-1H-pyrazol-5-yl]pyridine

IUPAC name

3-[1-(4-fluorophenyl)-3-(pyrrolidine-1-carbonyl)-1H-pyrazol-5-yl]pyridine

SMILES

O=C(c(cc1-c2cnccc2)nn1-c(cc1)ccc1F)N1CCCC1

InChI

InChI=1S/C19H17FN4O/c20-15-5-7-16(8-6-15)24-18(14-4-3-9-21-13-14)12-17(22-24)19(25)23-10-1-2-11-23/h3-9,12-13H,1-2,10-11H2

InChI Key

GNUUJDMJHKJWSU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27179431

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

336.37

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.797

Distribution Coefficient, logD

2.797

Water Solubility, LogSw

-2.78

Polar Surface Area

39.594

Acid Dissociation Constant (pKa)

28.00

Base Dissociation Constant (pKb)

3.19

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.10

F624-2827 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

BRD4 Targeted Library (4534 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

SH2 Library (10483 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Hemic and lymphatic
  • Cardiovascular
  • Metabolic
  • Cancer
  • Endocrine
Targets:
  • Others
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with F624-2827 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F624-2827?
Check Price and Availability of F624-2827, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F624-2827 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F624-2827
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F624-2827
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F624-2827 available by request