F624-2845 Screening compound: N-cyclohexyl-1-(4-fluorophenyl)-N-methyl-5-(pyridin-3-yl)-1H-pyrazole-3-carboxamide

F624-2845 Screening compound: N-cyclohexyl-1-(4-fluorophenyl)-N-methyl-5-(pyridin-3-yl)-1H-pyrazole-3-carboxamide
F624-2845 Screening compound: N-cyclohexyl-1-(4-fluorophenyl)-N-methyl-5-(pyridin-3-yl)-1H-pyrazole-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F624-2845
N-cyclohexyl-1-(4-fluorophenyl)-N-methyl-5-(pyridin-3-yl)-1H-pyrazole-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F624-2845

Molecular Formula

C22H23FN4O (C22 H23 FN4 O)

Compound Name

N-cyclohexyl-1-(4-fluorophenyl)-N-methyl-5-(pyridin-3-yl)-1H-pyrazole-3-carboxamide

IUPAC name

N-cyclohexyl-1-(4-fluorophenyl)-N-methyl-5-(pyridin-3-yl)-1H-pyrazole-3-carboxamide

SMILES

CN(C1CCCCC1)C(c(cc1-c2cnccc2)nn1-c(cc1)ccc1F)=O

InChI

InChI=1S/C22H23FN4O/c1-26(18-7-3-2-4-8-18)22(28)20-14-21(16-6-5-13-24-15-16)27(25-20)19-11-9-17(23)10-12-19/h5-6,9-15,18H,2-4,7-8H2,1H3

InChI Key

YVGBMCWZQFMMCB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27179444

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

378.45

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.814

Distribution Coefficient, logD

3.814

Water Solubility, LogSw

-3.64

Polar Surface Area

37.781

Acid Dissociation Constant (pKa)

27.48

Base Dissociation Constant (pKb)

3.19

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.80

F624-2845 in Drug Discovery

Included in Screening Libraries

BRD4 Targeted Library (4534 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS BBB Library (22607 compounds)

CNS Targets (44014 compounds)

Cardiovascular Library (22201 compounds)

SH2 Library (10483 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Cardiovascular
  • Metabolic
  • Nervous system
  • Nervous system
  • Cardiovascular
  • Cancer
  • Endocrine
Targets:
  • Others
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with F624-2845 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F624-2845?
Check Price and Availability of F624-2845, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F624-2845 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F624-2845
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F624-2845
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F624-2845 available by request