F624-2892 Screening compound: N-(3-cyanophenyl)-1-(4-fluorophenyl)-5-(pyridin-3-yl)-1H-pyrazole-3-carboxamide

F624-2892 Screening compound: N-(3-cyanophenyl)-1-(4-fluorophenyl)-5-(pyridin-3-yl)-1H-pyrazole-3-carboxamide
F624-2892 Screening compound: N-(3-cyanophenyl)-1-(4-fluorophenyl)-5-(pyridin-3-yl)-1H-pyrazole-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F624-2892
N-(3-cyanophenyl)-1-(4-fluorophenyl)-5-(pyridin-3-yl)-1H-pyrazole-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F624-2892

Molecular Formula

C22H14FN5O (C22 H14 FN5 O)

Compound Name

N-(3-cyanophenyl)-1-(4-fluorophenyl)-5-(pyridin-3-yl)-1H-pyrazole-3-carboxamide

IUPAC name

N-(3-cyanophenyl)-1-(4-fluorophenyl)-5-(pyridin-3-yl)-1H-pyrazole-3-carboxamide

SMILES

N#Cc1cccc(NC(c(cc2-c3cnccc3)nn2-c(cc2)ccc2F)=O)c1

InChI

InChI=1S/C22H14FN5O/c23-17-6-8-19(9-7-17)28-21(16-4-2-10-25-14-16)12-20(27-28)22(29)26-18-5-1-3-15(11-18)13-24/h1-12,14H,(H,26,29)

InChI Key

VPQLAMHDCBIGNQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27179471

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

383.38

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.686

Distribution Coefficient, logD

3.686

Water Solubility, LogSw

-3.95

Polar Surface Area

62.727

Acid Dissociation Constant (pKa)

11.17

Base Dissociation Constant (pKb)

3.19

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

F624-2892 in Drug Discovery

Included in Screening Libraries

BRD4 Targeted Library (4534 compounds)

Proline Kinase Library (2105 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Cardiovascular
  • Metabolic
  • Cancer
  • Digestive system
  • Nervous system
  • Male
  • Female
  • Endocrine
Targets:
  • Others
  • Kinases

References: we are preparing a list of scientific research reports with F624-2892 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F624-2892?
Check Price and Availability of F624-2892, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F624-2892 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F624-2892
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F624-2892
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F624-2892 available by request