F624-4724 Screening compound: 1-(4-fluorophenyl)-N-(4-methyl-1,3-thiazol-2-yl)-5-(pyridin-4-yl)-1H-pyrazole-3-carboxamide

F624-4724 Screening compound: 1-(4-fluorophenyl)-N-(4-methyl-1,3-thiazol-2-yl)-5-(pyridin-4-yl)-1H-pyrazole-3-carboxamide
F624-4724 Screening compound: 1-(4-fluorophenyl)-N-(4-methyl-1,3-thiazol-2-yl)-5-(pyridin-4-yl)-1H-pyrazole-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F624-4724
1-(4-fluorophenyl)-N-(4-methyl-1,3-thiazol-2-yl)-5-(pyridin-4-yl)-1H-pyrazole-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F624-4724

Molecular Formula

C19H14FN5OS (C19 H14 FN5 OS)

Compound Name

1-(4-fluorophenyl)-N-(4-methyl-1,3-thiazol-2-yl)-5-(pyridin-4-yl)-1H-pyrazole-3-carboxamide

IUPAC name

1-(4-fluorophenyl)-N-(4-methyl-13-thiazol-2-yl)-5-(pyridin-4-yl)-1H-pyrazole-3-carboxamide

SMILES

Cc1csc(NC(c(cc2-c3ccncc3)nn2-c(cc2)ccc2F)=O)n1

InChI

InChI=1S/C19H14FN5OS/c1-12-11-27-19(22-12)23-18(26)16-10-17(13-6-8-21-9-7-13)25(24-16)15-4-2-14(20)3-5-15/h2-11H,1H3,(H,22,23,26)

InChI Key

OLWWLZOJYXXIFK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27179601

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

379.42

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.714

Distribution Coefficient, logD

3.709

Water Solubility, LogSw

-3.82

Polar Surface Area

55.434

Acid Dissociation Constant (pKa)

9.44

Base Dissociation Constant (pKb)

3.60

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.30

F624-4724 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Angiogenesis library (14822 compounds)

Antiviral Library (67538 compounds)

CNS Targets (44014 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

SH2 Library (10483 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Targeted Diversity Library (40567 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Antiviral
  • Infections
  • Immune system
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Endocrine
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases
  • Kinases
  • Proteases
  • Kinases
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with F624-4724 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F624-4724?
Check Price and Availability of F624-4724, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F624-4724 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F624-4724
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F624-4724
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F624-4724 available by request