F632-1265 Screening compound: 6-chloro-7-{[2-(1,2,3,4-tetrahydroisoquinoline-2-carbonyl)pyrrolidin-1-yl]sulfonyl}-3,4-dihydro-2H-1,4-benzoxazin-3-one

F632-1265 Screening compound: 6-chloro-7-{[2-(1,2,3,4-tetrahydroisoquinoline-2-carbonyl)pyrrolidin-1-yl]sulfonyl}-3,4-dihydro-2H-1,4-benzoxazin-3-one
F632-1265 Screening compound: 6-chloro-7-{[2-(1,2,3,4-tetrahydroisoquinoline-2-carbonyl)pyrrolidin-1-yl]sulfonyl}-3,4-dihydro-2H-1,4-benzoxazin-3-one alternative view

Chemical Structure Depiction of ChemDiv screening compound F632-1265
6-chloro-7-{[2-(1,2,3,4-tetrahydroisoquinoline-2-carbonyl)pyrrolidin-1-yl]sulfonyl}-3,4-dihydro-2H-1,4-benzoxazin-3-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F632-1265

Molecular Formula

C22H22ClN3O5S (C22 H22 ClN3 O5 S)

Compound Name

6-chloro-7-{[2-(1,2,3,4-tetrahydroisoquinoline-2-carbonyl)pyrrolidin-1-yl]sulfonyl}-3,4-dihydro-2H-1,4-benzoxazin-3-one

IUPAC name

6-chloro-7-{[2-(1234-tetrahydroisoquinoline-2-carbonyl)pyrrolidin-1-yl]sulfonyl}-34-dihydro-2H-14-benzoxazin-3-one

SMILES

O=C(C(CCC1)N1S(c(cc(c(N1)c2)OCC1=O)c2Cl)(=O)=O)N(CC1)Cc2c1cccc2

InChI

InChI=1S/C22H22ClN3O5S/c23-16-10-17-19(31-13-21(27)24-17)11-20(16)32(29,30)26-8-3-6-18(26)22(28)25-9-7-14-4-1-2-5-15(14)12-25/h1-2,4-5,10-11,18H,3,6-9,12-13H2,(H,24,27)/t18-/m0/s1

InChI Key

PWSCLGPWIWFLNV-SFHVURJKSA-N

MDL Number (MFCD)

MFCD27180480

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

475.95

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.135

Distribution Coefficient, logD

2.077

Water Solubility, LogSw

-3.10

Polar Surface Area

82.367

Acid Dissociation Constant (pKa)

8.24

Base Dissociation Constant (pKb)

-3.90

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

36.40

F632-1265 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Antiviral HBV Library (10007 compounds)

Antiviral Library (67538 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Targeted Diversity Library (40567 compounds)

Anti-HIV1 Library (19540 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with F632-1265 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F632-1265?
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What is the minimum amount of F632-1265 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F632-1265
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F632-1265
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F632-1265 available by request