F653-0176 Screening compound: N-{2,4-bis[(4-methoxyphenyl)amino]-6-methylpyrimidin-5-yl}butanamide

F653-0176 Screening compound: N-{2,4-bis[(4-methoxyphenyl)amino]-6-methylpyrimidin-5-yl}butanamide
F653-0176 Screening compound: N-{2,4-bis[(4-methoxyphenyl)amino]-6-methylpyrimidin-5-yl}butanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F653-0176
N-{2,4-bis[(4-methoxyphenyl)amino]-6-methylpyrimidin-5-yl}butanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F653-0176

Molecular Formula

C23H27N5O3 (C23 H27 N5 O3)

Compound Name

N-{2,4-bis[(4-methoxyphenyl)amino]-6-methylpyrimidin-5-yl}butanamide

IUPAC name

N-{24-bis[(4-methoxyphenyl)amino]-6-methylpyrimidin-5-yl}butanamide

SMILES

CCCC(Nc1c(Nc(cc2)ccc2OC)nc(Nc(cc2)ccc2OC)nc1C)=O

InChI

InChI=1S/C23H27N5O3/c1-5-6-20(29)27-21-15(2)24-23(26-17-9-13-19(31-4)14-10-17)28-22(21)25-16-7-11-18(30-3)12-8-16/h7-14H,5-6H2,1-4H3,(H,27,29)(H2,24,25,26,28)

InChI Key

LUJZNERPKSTKPL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27183027

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

421.5

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.501

Distribution Coefficient, logD

4.216

Water Solubility, LogSw

-4.29

Polar Surface Area

75.827

Acid Dissociation Constant (pKa)

10.76

Base Dissociation Constant (pKb)

7.37

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.10

F653-0176 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Anticancer Library (62698 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Cancer
  • Digestive system
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • Epigenetic
Targets:
  • Proteases
  • Kinases

References: we are preparing a list of scientific research reports with F653-0176 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F653-0176?
Check Price and Availability of F653-0176, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F653-0176 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F653-0176
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F653-0176
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F653-0176 available by request