F666-0911 Screening compound: 3,6-dimethyl-1-phenyl-5-[4-(4-phenylpiperazine-1-carbonyl)piperidin-1-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione

F666-0911 Screening compound: 3,6-dimethyl-1-phenyl-5-[4-(4-phenylpiperazine-1-carbonyl)piperidin-1-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
F666-0911 Screening compound: 3,6-dimethyl-1-phenyl-5-[4-(4-phenylpiperazine-1-carbonyl)piperidin-1-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound F666-0911
3,6-dimethyl-1-phenyl-5-[4-(4-phenylpiperazine-1-carbonyl)piperidin-1-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F666-0911

Molecular Formula

C28H33N5O3 (C28 H33 N5 O3)

Compound Name

3,6-dimethyl-1-phenyl-5-[4-(4-phenylpiperazine-1-carbonyl)piperidin-1-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione

IUPAC name

36-dimethyl-1-phenyl-5-[4-(4-phenylpiperazine-1-carbonyl)piperidin-1-yl]-1234-tetrahydropyrimidine-24-dione

SMILES

CC(N(c1ccccc1)C(N(C)C1=O)=O)=C1N(CC1)CCC1C(N(CC1)CCN1c1ccccc1)=O

InChI

InChI=1S/C28H33N5O3/c1-21-25(27(35)29(2)28(36)33(21)24-11-7-4-8-12-24)31-15-13-22(14-16-31)26(34)32-19-17-30(18-20-32)23-9-5-3-6-10-23/h3-12,22H,13-20H2,1-2H3

InChI Key

SJRVXUFMEZTDDU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27183094

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

487.6

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.961

Distribution Coefficient, logD

2.455

Water Solubility, LogSw

-2.94

Polar Surface Area

54.473

Acid Dissociation Constant (pKa)

23.62

Base Dissociation Constant (pKb)

3.23

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

39.30

F666-0911 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Targeted Diversity Library (40567 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with F666-0911 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F666-0911?
Check Price and Availability of F666-0911, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F666-0911 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F666-0911
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F666-0911
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F666-0911 available by request