F668-0903 Screening compound: 1,3,8-trimethyl-N-({1-[(4-methylphenyl)methyl]piperidin-4-yl}methyl)-2,4,7-trioxo-1H,2H,3H,4H,7H,8H-pyrido[2,3-d]pyrimidine-5-carboxamide

F668-0903 Screening compound: 1,3,8-trimethyl-N-({1-[(4-methylphenyl)methyl]piperidin-4-yl}methyl)-2,4,7-trioxo-1H,2H,3H,4H,7H,8H-pyrido[2,3-d]pyrimidine-5-carboxamide
F668-0903 Screening compound: 1,3,8-trimethyl-N-({1-[(4-methylphenyl)methyl]piperidin-4-yl}methyl)-2,4,7-trioxo-1H,2H,3H,4H,7H,8H-pyrido[2,3-d]pyrimidine-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F668-0903
1,3,8-trimethyl-N-({1-[(4-methylphenyl)methyl]piperidin-4-yl}methyl)-2,4,7-trioxo-1H,2H,3H,4H,7H,8H-pyrido[2,3-d]pyrimidine-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F668-0903

Molecular Formula

C25H31N5O4 (C25 H31 N5 O4)

Compound Name

1,3,8-trimethyl-N-({1-[(4-methylphenyl)methyl]piperidin-4-yl}methyl)-2,4,7-trioxo-1H,2H,3H,4H,7H,8H-pyrido[2,3-d]pyrimidine-5-carboxamide

IUPAC name

138-trimethyl-N-({1-[(4-methylphenyl)methyl]piperidin-4-yl}methyl)-247-trioxo-1H2H3H4H7H8H-pyrido[23-d]pyrimidine-5-carboxamide

SMILES

Cc1ccc(CN2CCC(CNC(C(C(C(N3C)=O)=C(N4C)N(C)C3=O)=CC4=O)=O)CC2)cc1

InChI

InChI=1S/C25H31N5O4/c1-16-5-7-18(8-6-16)15-30-11-9-17(10-12-30)14-26-22(32)19-13-20(31)27(2)23-21(19)24(33)29(4)25(34)28(23)3/h5-8,13,17H,9-12,14-15H2,1-4H3,(H,26,32)

InChI Key

MNPYXENZYHXFHH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27183396

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

465.55

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.570

Distribution Coefficient, logD

-1.151

Water Solubility, LogSw

-2.28

Polar Surface Area

75.750

Acid Dissociation Constant (pKa)

12.18

Base Dissociation Constant (pKb)

10.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

44.00

F668-0903 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with F668-0903 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F668-0903?
Check Price and Availability of F668-0903, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F668-0903 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F668-0903
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F668-0903
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F668-0903 available by request