F668-0922 Screening compound: 1,3,8-trimethyl-2,4,7-trioxo-N-({1-[2-(thiophen-2-yl)ethyl]piperidin-4-yl}methyl)-1H,2H,3H,4H,7H,8H-pyrido[2,3-d]pyrimidine-5-carboxamide

F668-0922 Screening compound: 1,3,8-trimethyl-2,4,7-trioxo-N-({1-[2-(thiophen-2-yl)ethyl]piperidin-4-yl}methyl)-1H,2H,3H,4H,7H,8H-pyrido[2,3-d]pyrimidine-5-carboxamide
F668-0922 Screening compound: 1,3,8-trimethyl-2,4,7-trioxo-N-({1-[2-(thiophen-2-yl)ethyl]piperidin-4-yl}methyl)-1H,2H,3H,4H,7H,8H-pyrido[2,3-d]pyrimidine-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F668-0922
1,3,8-trimethyl-2,4,7-trioxo-N-({1-[2-(thiophen-2-yl)ethyl]piperidin-4-yl}methyl)-1H,2H,3H,4H,7H,8H-pyrido[2,3-d]pyrimidine-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F668-0922

Molecular Formula

C23H29N5O4S (C23 H29 N5 O4 S)

Compound Name

1,3,8-trimethyl-2,4,7-trioxo-N-({1-[2-(thiophen-2-yl)ethyl]piperidin-4-yl}methyl)-1H,2H,3H,4H,7H,8H-pyrido[2,3-d]pyrimidine-5-carboxamide

IUPAC name

138-trimethyl-247-trioxo-N-({1-[2-(thiophen-2-yl)ethyl]piperidin-4-yl}methyl)-1H2H3H4H7H8H-pyrido[23-d]pyrimidine-5-carboxamide

SMILES

CN(C(C=C1C(NCC2CCN(CCc3cccs3)CC2)=O)=O)C(N(C)C(N2C)=O)=C1C2=O

InChI

InChI=1S/C23H29N5O4S/c1-25-18(29)13-17(19-21(25)26(2)23(32)27(3)22(19)31)20(30)24-14-15-6-9-28(10-7-15)11-8-16-5-4-12-33-16/h4-5,12-13,15H,6-11,14H2,1-3H3,(H,24,30)

InChI Key

OWWMGAABCIWBJM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27183409

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

471.58

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.317

Distribution Coefficient, logD

-0.642

Water Solubility, LogSw

-2.24

Polar Surface Area

76.747

Acid Dissociation Constant (pKa)

12.18

Base Dissociation Constant (pKb)

9.35

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

47.80

F668-0922 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

GPCR Targeted Library (31838 compounds)

Antibacterial Compounds Library (13827 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Infections
  • Immune system
  • animal
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F668-0922 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F668-0922?
Check Price and Availability of F668-0922, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F668-0922 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F668-0922
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F668-0922
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F668-0922 available by request