F674-0409 Screening compound: N-[2-(1H-INDOL-3-YL)ETHYL]-1-{4-METHYL-3-OXO-3H,4H-PYRIDO[2,3-B]PYRAZIN-2-YL}PIPERIDINE-4-CARBOXAMIDE

F674-0409 Screening compound: N-[2-(1H-INDOL-3-YL)ETHYL]-1-{4-METHYL-3-OXO-3H,4H-PYRIDO[2,3-B]PYRAZIN-2-YL}PIPERIDINE-4-CARBOXAMIDE
F674-0409 Screening compound: N-[2-(1H-INDOL-3-YL)ETHYL]-1-{4-METHYL-3-OXO-3H,4H-PYRIDO[2,3-B]PYRAZIN-2-YL}PIPERIDINE-4-CARBOXAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound F674-0409
N-[2-(1H-INDOL-3-YL)ETHYL]-1-{4-METHYL-3-OXO-3H,4H-PYRIDO[2,3-B]PYRAZIN-2-YL}PIPERIDINE-4-CARBOXAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F674-0409

Molecular Formula

C24H26N6O2 (C24 H26 N6 O2)

Compound Name

N-[2-(1H-INDOL-3-YL)ETHYL]-1-{4-METHYL-3-OXO-3H,4H-PYRIDO[2,3-B]PYRAZIN-2-YL}PIPERIDINE-4-CARBOXAMIDE

IUPAC name

n/a

SMILES

CN(c1ncccc1N=C1N(CC2)CCC2C(NCCc2c[nH]c3c2cccc3)=O)C1=O

InChI

InChI=1S/C24H26N6O2/c1-29-21-20(7-4-11-25-21)28-22(24(29)32)30-13-9-16(10-14-30)23(31)26-12-8-17-15-27-19-6-3-2-5-18(17)19/h2-7,11,15-16,27H,8-10,12-14H2,1H3,(H,26,31)

InChI Key

KJRLOPAMANLEOE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27183701

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

430.51

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.691

Distribution Coefficient, logD

1.686

Water Solubility, LogSw

-1.99

Polar Surface Area

70.714

Acid Dissociation Constant (pKa)

13.87

Base Dissociation Constant (pKb)

5.50

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

F674-0409 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Cardiovascular
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Proteases
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with F674-0409 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F674-0409?
Check Price and Availability of F674-0409, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F674-0409 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F674-0409
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F674-0409
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F674-0409 available by request