F674-0499 Screening compound: N-[(3-bromophenyl)methyl]-1-{4-methyl-3-oxo-3H,4H-pyrido[2,3-b]pyrazin-2-yl}piperidine-4-carboxamide

F674-0499 Screening compound: N-[(3-bromophenyl)methyl]-1-{4-methyl-3-oxo-3H,4H-pyrido[2,3-b]pyrazin-2-yl}piperidine-4-carboxamide
F674-0499 Screening compound: N-[(3-bromophenyl)methyl]-1-{4-methyl-3-oxo-3H,4H-pyrido[2,3-b]pyrazin-2-yl}piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F674-0499
N-[(3-bromophenyl)methyl]-1-{4-methyl-3-oxo-3H,4H-pyrido[2,3-b]pyrazin-2-yl}piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F674-0499

Molecular Formula

C21H22BrN5O2 (C21 H22 BrN5 O2)

Compound Name

N-[(3-bromophenyl)methyl]-1-{4-methyl-3-oxo-3H,4H-pyrido[2,3-b]pyrazin-2-yl}piperidine-4-carboxamide

IUPAC name

N-[(3-bromophenyl)methyl]-1-{4-methyl-3-oxo-3H4H-pyrido[23-b]pyrazin-2-yl}piperidine-4-carboxamide

SMILES

CN(c(nccc1)c1N=C1N(CC2)CCC2C(NCc2cccc(Br)c2)=O)C1=O

InChI

InChI=1S/C21H22BrN5O2/c1-26-18-17(6-3-9-23-18)25-19(21(26)29)27-10-7-15(8-11-27)20(28)24-13-14-4-2-5-16(22)12-14/h2-6,9,12,15H,7-8,10-11,13H2,1H3,(H,24,28)

InChI Key

NCZDOEARFFXRNH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27183730

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

456.34

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.919

Distribution Coefficient, logD

1.914

Water Solubility, LogSw

-2.38

Polar Surface Area

61.001

Acid Dissociation Constant (pKa)

12.56

Base Dissociation Constant (pKb)

5.50

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

F674-0499 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with F674-0499 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F674-0499?
Check Price and Availability of F674-0499, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F674-0499 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F674-0499
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F674-0499
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F674-0499 available by request