F677-0064 Screening compound: 1-{4-benzyl-3-oxo-3H,4H-pyrido[2,3-b]pyrazin-2-yl}-N-[2-(piperidin-1-yl)ethyl]piperidine-3-carboxamide

F677-0064 Screening compound: 1-{4-benzyl-3-oxo-3H,4H-pyrido[2,3-b]pyrazin-2-yl}-N-[2-(piperidin-1-yl)ethyl]piperidine-3-carboxamide
F677-0064 Screening compound: 1-{4-benzyl-3-oxo-3H,4H-pyrido[2,3-b]pyrazin-2-yl}-N-[2-(piperidin-1-yl)ethyl]piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F677-0064
1-{4-benzyl-3-oxo-3H,4H-pyrido[2,3-b]pyrazin-2-yl}-N-[2-(piperidin-1-yl)ethyl]piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F677-0064

Molecular Formula

C27H34N6O2 (C27 H34 N6 O2)

Compound Name

1-{4-benzyl-3-oxo-3H,4H-pyrido[2,3-b]pyrazin-2-yl}-N-[2-(piperidin-1-yl)ethyl]piperidine-3-carboxamide

IUPAC name

1-{4-benzyl-3-oxo-3H4H-pyrido[23-b]pyrazin-2-yl}-N-[2-(piperidin-1-yl)ethyl]piperidine-3-carboxamide

SMILES

O=C(C(CCC1)CN1C1=Nc2cccnc2N(Cc2ccccc2)C1=O)NCCN1CCCCC1

InChI

InChI=1S/C27H34N6O2/c34-26(29-14-18-31-15-5-2-6-16-31)22-11-8-17-32(20-22)25-27(35)33(19-21-9-3-1-4-10-21)24-23(30-25)12-7-13-28-24/h1,3-4,7,9-10,12-13,22H,2,5-6,8,11,14-20H2,(H,29,34)/t22-/m0/s1

InChI Key

DPWHGCJZJKYARB-QFIPXVFZSA-N

MDL Number (MFCD)

MFCD27183818

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

474.61

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.458

Distribution Coefficient, logD

0.650

Water Solubility, LogSw

-2.68

Polar Surface Area

64.722

Acid Dissociation Constant (pKa)

13.28

Base Dissociation Constant (pKb)

9.20

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

48.10

F677-0064 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with F677-0064 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F677-0064?
Check Price and Availability of F677-0064, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F677-0064 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F677-0064
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F677-0064
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F677-0064 available by request