F677-0119 Screening compound: 1-{4-benzyl-3-oxo-3H,4H-pyrido[2,3-b]pyrazin-2-yl}-N-[(3-fluorophenyl)methyl]piperidine-3-carboxamide

F677-0119 Screening compound: 1-{4-benzyl-3-oxo-3H,4H-pyrido[2,3-b]pyrazin-2-yl}-N-[(3-fluorophenyl)methyl]piperidine-3-carboxamide
F677-0119 Screening compound: 1-{4-benzyl-3-oxo-3H,4H-pyrido[2,3-b]pyrazin-2-yl}-N-[(3-fluorophenyl)methyl]piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F677-0119
1-{4-benzyl-3-oxo-3H,4H-pyrido[2,3-b]pyrazin-2-yl}-N-[(3-fluorophenyl)methyl]piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F677-0119

Molecular Formula

C27H26FN5O2 (C27 H26 FN5 O2)

Compound Name

1-{4-benzyl-3-oxo-3H,4H-pyrido[2,3-b]pyrazin-2-yl}-N-[(3-fluorophenyl)methyl]piperidine-3-carboxamide

IUPAC name

1-{4-benzyl-3-oxo-3H4H-pyrido[23-b]pyrazin-2-yl}-N-[(3-fluorophenyl)methyl]piperidine-3-carboxamide

SMILES

O=C(C(CCC1)CN1C(C(N1Cc2ccccc2)=O)=Nc2c1nccc2)NCc1cccc(F)c1

InChI

InChI=1S/C27H26FN5O2/c28-22-11-4-9-20(15-22)16-30-26(34)21-10-6-14-32(18-21)25-27(35)33(17-19-7-2-1-3-8-19)24-23(31-25)12-5-13-29-24/h1-5,7-9,11-13,15,21H,6,10,14,16-18H2,(H,30,34)/t21-/m0/s1

InChI Key

JSTWONMDGHEHMJ-NRFANRHFSA-N

MDL Number (MFCD)

MFCD27183846

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

471.53

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.202

Distribution Coefficient, logD

3.202

Water Solubility, LogSw

-3.36

Polar Surface Area

60.898

Acid Dissociation Constant (pKa)

12.49

Base Dissociation Constant (pKb)

3.04

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

25.90

F677-0119 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with F677-0119 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F677-0119?
Check Price and Availability of F677-0119, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F677-0119 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F677-0119
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F677-0119
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F677-0119 available by request