F677-0204 Screening compound: 2-[3-(4-benzylpiperidine-1-carbonyl)piperidin-1-yl]-4-ethyl-3H,4H-pyrido[2,3-b]pyrazin-3-one

F677-0204 Screening compound: 2-[3-(4-benzylpiperidine-1-carbonyl)piperidin-1-yl]-4-ethyl-3H,4H-pyrido[2,3-b]pyrazin-3-one
F677-0204 Screening compound: 2-[3-(4-benzylpiperidine-1-carbonyl)piperidin-1-yl]-4-ethyl-3H,4H-pyrido[2,3-b]pyrazin-3-one alternative view

Chemical Structure Depiction of ChemDiv screening compound F677-0204
2-[3-(4-benzylpiperidine-1-carbonyl)piperidin-1-yl]-4-ethyl-3H,4H-pyrido[2,3-b]pyrazin-3-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F677-0204

Molecular Formula

C27H33N5O2 (C27 H33 N5 O2)

Compound Name

2-[3-(4-benzylpiperidine-1-carbonyl)piperidin-1-yl]-4-ethyl-3H,4H-pyrido[2,3-b]pyrazin-3-one

IUPAC name

2-[3-(4-benzylpiperidine-1-carbonyl)piperidin-1-yl]-4-ethyl-3H4H-pyrido[23-b]pyrazin-3-one

SMILES

CCN(c1ncccc1N=C1N(CCC2)CC2C(N2CCC(Cc3ccccc3)CC2)=O)C1=O

InChI

InChI=1S/C27H33N5O2/c1-2-32-24-23(11-6-14-28-24)29-25(27(32)34)31-15-7-10-22(19-31)26(33)30-16-12-21(13-17-30)18-20-8-4-3-5-9-20/h3-6,8-9,11,14,21-22H,2,7,10,12-13,15-19H2,1H3

InChI Key

YKOOBRNKOOXJIX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27183866

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

459.59

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.566

Distribution Coefficient, logD

3.566

Water Solubility, LogSw

-3.57

Polar Surface Area

52.857

Acid Dissociation Constant (pKa)

22.98

Base Dissociation Constant (pKb)

4.21

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

48.10

F677-0204 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with F677-0204 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F677-0204?
Check Price and Availability of F677-0204, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F677-0204 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F677-0204
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F677-0204
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F677-0204 available by request