F708-0412 Screening compound: N1-(5-chloro-2-methylphenyl)-4-methyl-N4-[(4-methylphenyl)methyl]piperidine-1,4-dicarboxamide

F708-0412 Screening compound: N1-(5-chloro-2-methylphenyl)-4-methyl-N4-[(4-methylphenyl)methyl]piperidine-1,4-dicarboxamide
F708-0412 Screening compound: N1-(5-chloro-2-methylphenyl)-4-methyl-N4-[(4-methylphenyl)methyl]piperidine-1,4-dicarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F708-0412
N1-(5-chloro-2-methylphenyl)-4-methyl-N4-[(4-methylphenyl)methyl]piperidine-1,4-dicarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F708-0412

Molecular Formula

C23H28ClN3O2 (C23 H28 ClN3 O2)

Compound Name

N1-(5-chloro-2-methylphenyl)-4-methyl-N4-[(4-methylphenyl)methyl]piperidine-1,4-dicarboxamide

IUPAC name

N1-(5-chloro-2-methylphenyl)-4-methyl-N4-[(4-methylphenyl)methyl]piperidine-14-dicarboxamide

SMILES

CC(CC1)(CCN1C(Nc1c(C)ccc(Cl)c1)=O)C(NCc1ccc(C)cc1)=O

InChI

InChI=1S/C23H28ClN3O2/c1-16-4-7-18(8-5-16)15-25-21(28)23(3)10-12-27(13-11-23)22(29)26-20-14-19(24)9-6-17(20)2/h4-9,14H,10-13,15H2,1-3H3,(H,25,28)(H,26,29)

InChI Key

WSNDZRGSHPAIJD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27186724

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

413.95

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.328

Distribution Coefficient, logD

4.328

Water Solubility, LogSw

-4.46

Polar Surface Area

49.423

Acid Dissociation Constant (pKa)

11.91

Base Dissociation Constant (pKb)

-3.41

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

39.10

F708-0412 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

KRAS-Targeted Library (16000 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Hemic and lymphatic
  • Cardiovascular
  • Antiviral
  • Infections
  • Immune system
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with F708-0412 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F708-0412?
Check Price and Availability of F708-0412, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F708-0412 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F708-0412
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F708-0412
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F708-0412 available by request