F723-0418 Screening compound: 2-{[1,4'-bipiperidin]-1'-yl}-6-(3-methylbenzamido)quinoline-4-carboxylic acid

Chemical Structure Depiction of ChemDiv screening compound F723-0418
2-{[1,4'-bipiperidin]-1'-yl}-6-(3-methylbenzamido)quinoline-4-carboxylic acid

Available from 1 mg

Formats:

Glass Vials (4ml Glass Vials VWR #97047-678)
96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Check Price and Availability

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F723-0418

Molecular Formula

C₂₈H₃₂N₄O₃ (C28 H32 N4 O3)

Compound Name

2-{[1,4'-bipiperidin]-1'-yl}-6-(3-methylbenzamido)quinoline-4-carboxylic acid

IUPAC name

2-{[14'-bipiperidin]-1'-yl}-6-(3-methylbenzamido)quinoline-4-carboxylic acid

SMILES

Cc1cccc(C(Nc(cc2c(C(O)=O)c3)ccc2nc3N(CC2)CCC2N2CCCCC2)=O)c1

InChI

InChI=1S/C28H32N4O3/c1-19-6-5-7-20(16-19)27(33)29-21-8-9-25-23(17-21)24(28(34)35)18-26(30-25)32-14-10-22(11-15-32)31-12-3-2-4-13-31/h5-9,16-18,22H,2-4,10-15H2,1H3,(H,29,33)(H,34,35)

InChI Key

HYYLFZBUCAQAFP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27187728

Chemical and Physical Properties

Saltdata

2HCl

Molecular Weight

472.59

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

Partition Coefficient, logP

5.669

Distribution Coefficient, logD

5.669

Water Solubility, LogSw

-5.35

Polar Surface Area

66.078

Acid Dissociation Constant (pK_a)

4.46

Base Dissociation Constant (pK_b)

9.96

Number of Chiral Centers

0.00

Percent sp³ carbon bonding

39.30

F723-0418 in Drug Discovery

Included in Screening Libraries

Anti-infective Library (19449 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Protein-Protein Interaction Library (218420 compounds)

RAR (Nuclear receptors) Ligands Library (6524 compounds)

Targeted Diversity Library (40567 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Peptidomimetic Library (37031 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:

Infections
Immune system
animal
Hemic and lymphatic
Cardiovascular
Cancer
Digestive system
Respiratory tract
Otorhinolaryngologic
Nervous system
Hemic and lymphatic
Cardiovascular
Cancer
Respiratory tract
Eye
Male
Female
Hemic and lymphatic
Congenital
Skin
Endocrine
Immune system
Cancer
Nervous system
Hemic and lymphatic
Endocrine
Immune system
Cancer
Nervous system
Male
Female
Hemic and lymphatic
Skin
Endocrine

Targets:

Kinases
Nuclear receptors
Phosphatases

Mechanism of action:

PPI modulators
Receptor's ligands
Epigenetic
PPI modulators

Structure:

Mimetics

References: we are preparing a list of scientific research reports with F723-0418 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F723-0418?
Check Price and Availability of F723-0418, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.

What is the minimum amount of F723-0418 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.

Delivery options for F723-0418
ChemDiv sends parcels with Express services (UPS, WC).

1–2 days for small orders
2–4 weeks for large selections

Delivery formats for F723-0418

0.5–50 mg of dry powder sample in single glass vials, custom vials
DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F723-0418 available by request