F723-0457 Screening compound: 6-(4-bromobenzamido)-2-[butyl(methyl)amino]quinoline-4-carboxylic acid

F723-0457 Screening compound: 6-(4-bromobenzamido)-2-[butyl(methyl)amino]quinoline-4-carboxylic acid
F723-0457 Screening compound: 6-(4-bromobenzamido)-2-[butyl(methyl)amino]quinoline-4-carboxylic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound F723-0457
6-(4-bromobenzamido)-2-[butyl(methyl)amino]quinoline-4-carboxylic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F723-0457

Molecular Formula

C22H22BrN3O3 (C22 H22 BrN3 O3)

Compound Name

6-(4-bromobenzamido)-2-[butyl(methyl)amino]quinoline-4-carboxylic acid

IUPAC name

6-(4-bromobenzamido)-2-[butyl(methyl)amino]quinoline-4-carboxylic acid

SMILES

CCCCN(C)c1cc(C(O)=O)c(cc(cc2)NC(c(cc3)ccc3Br)=O)c2n1

InChI

InChI=1S/C22H22BrN3O3/c1-3-4-11-26(2)20-13-18(22(28)29)17-12-16(9-10-19(17)25-20)24-21(27)14-5-7-15(23)8-6-14/h5-10,12-13H,3-4,11H2,1-2H3,(H,24,27)(H,28,29)

InChI Key

GLWLQGGPYUPUEW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14964572

Chemical and Physical Properties

Saltdata

2HCl

Molecular Weight

456.34

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.668

Distribution Coefficient, logD

2.724

Water Solubility, LogSw

-5.36

Polar Surface Area

62.737

Acid Dissociation Constant (pKa)

4.46

Base Dissociation Constant (pKb)

3.43

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.70

F723-0457 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

RAR (Nuclear receptors) Ligands Library (6524 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Respiratory tract
  • Eye
  • Male
  • Female
  • Hemic and lymphatic
  • Congenital
  • Skin
  • Endocrine
  • Immune system
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F723-0457 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F723-0457?
Check Price and Availability of F723-0457, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F723-0457 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F723-0457
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F723-0457
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F723-0457 available by request