F723-0649 Screening compound: 6-(4-bromobenzamido)-2-(3-methylpiperidin-1-yl)quinoline-4-carboxylic acid

F723-0649 Screening compound: 6-(4-bromobenzamido)-2-(3-methylpiperidin-1-yl)quinoline-4-carboxylic acid
F723-0649 Screening compound: 6-(4-bromobenzamido)-2-(3-methylpiperidin-1-yl)quinoline-4-carboxylic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound F723-0649
6-(4-bromobenzamido)-2-(3-methylpiperidin-1-yl)quinoline-4-carboxylic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F723-0649

Molecular Formula

C23H22BrN3O3 (C23 H22 BrN3 O3)

Compound Name

6-(4-bromobenzamido)-2-(3-methylpiperidin-1-yl)quinoline-4-carboxylic acid

IUPAC name

6-(4-bromobenzamido)-2-(3-methylpiperidin-1-yl)quinoline-4-carboxylic acid

SMILES

CC(CCC1)CN1c1cc(C(O)=O)c(cc(cc2)NC(c(cc3)ccc3Br)=O)c2n1

InChI

InChI=1S/C23H22BrN3O3/c1-14-3-2-10-27(13-14)21-12-19(23(29)30)18-11-17(8-9-20(18)26-21)25-22(28)15-4-6-16(24)7-5-15/h4-9,11-12,14H,2-3,10,13H2,1H3,(H,25,28)(H,29,30)/t14-/m0/s1

InChI Key

VKBQLSPHZGTQNX-AWEZNQCLSA-N

MDL Number (MFCD)

MFCD14964593

Chemical and Physical Properties

Saltdata

2HCl

Molecular Weight

468.35

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.906

Distribution Coefficient, logD

2.962

Water Solubility, LogSw

-5.50

Polar Surface Area

62.918

Acid Dissociation Constant (pKa)

4.46

Base Dissociation Constant (pKb)

2.95

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

26.10

F723-0649 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein-Protein Interaction Library (218420 compounds)

RAR (Nuclear receptors) Ligands Library (6524 compounds)

SmartTM Library (51161 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Respiratory tract
  • Eye
  • Male
  • Female
  • Hemic and lymphatic
  • Congenital
  • Skin
  • Endocrine
  • Immune system
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
  • Epigenetic
Targets:
  • Nuclear receptors

References: we are preparing a list of scientific research reports with F723-0649 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F723-0649?
Check Price and Availability of F723-0649, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F723-0649 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F723-0649
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F723-0649
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F723-0649 available by request