F723-1058 Screening compound: 6-(4-fluorobenzamido)-2-[3-(2-methylphenyl)pyrrolidin-1-yl]quinoline-4-carboxylic acid

F723-1058 Screening compound: 6-(4-fluorobenzamido)-2-[3-(2-methylphenyl)pyrrolidin-1-yl]quinoline-4-carboxylic acid
F723-1058 Screening compound: 6-(4-fluorobenzamido)-2-[3-(2-methylphenyl)pyrrolidin-1-yl]quinoline-4-carboxylic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound F723-1058
6-(4-fluorobenzamido)-2-[3-(2-methylphenyl)pyrrolidin-1-yl]quinoline-4-carboxylic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F723-1058

Molecular Formula

C28H24FN3O3 (C28 H24 FN3 O3)

Compound Name

6-(4-fluorobenzamido)-2-[3-(2-methylphenyl)pyrrolidin-1-yl]quinoline-4-carboxylic acid

IUPAC name

6-(4-fluorobenzamido)-2-[3-(2-methylphenyl)pyrrolidin-1-yl]quinoline-4-carboxylic acid

SMILES

Cc1c(C(CC2)CN2c2cc(C(O)=O)c(cc(cc3)NC(c(cc4)ccc4F)=O)c3n2)cccc1

InChI

InChI=1S/C28H24FN3O3/c1-17-4-2-3-5-22(17)19-12-13-32(16-19)26-15-24(28(34)35)23-14-21(10-11-25(23)31-26)30-27(33)18-6-8-20(29)9-7-18/h2-11,14-15,19H,12-13,16H2,1H3,(H,30,33)(H,34,35)/t19-/m1/s1

InChI Key

AVUAMPSFYDCKAN-LJQANCHMSA-N

MDL Number (MFCD)

MFCD27187751

Chemical and Physical Properties

Saltdata

2HCl

Molecular Weight

469.52

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

6.314

Distribution Coefficient, logD

3.370

Water Solubility, LogSw

-5.46

Polar Surface Area

63.012

Acid Dissociation Constant (pKa)

4.46

Base Dissociation Constant (pKb)

1.92

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

17.90

F723-1058 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

Immunological Library (6760 compounds)

RAR (Nuclear receptors) Ligands Library (6524 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

PD-1/L1 Library (498 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Immune system
  • Cancer
  • Respiratory tract
  • Eye
  • Male
  • Female
  • Hemic and lymphatic
  • Congenital
  • Skin
  • Endocrine
  • Immune system
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
  • Cancer
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Targets:
  • Nuclear receptors
  • Others
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with F723-1058 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F723-1058?
Check Price and Availability of F723-1058, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F723-1058 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F723-1058
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F723-1058
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F723-1058 available by request