F724-0021 Screening compound: 2-[4-(4-methoxyphenyl)piperazin-1-yl]-6-(4-methylbenzamido)quinoline-4-carboxylic acid

F724-0021 Screening compound: 2-[4-(4-methoxyphenyl)piperazin-1-yl]-6-(4-methylbenzamido)quinoline-4-carboxylic acid
F724-0021 Screening compound: 2-[4-(4-methoxyphenyl)piperazin-1-yl]-6-(4-methylbenzamido)quinoline-4-carboxylic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound F724-0021
2-[4-(4-methoxyphenyl)piperazin-1-yl]-6-(4-methylbenzamido)quinoline-4-carboxylic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F724-0021

Molecular Formula

C29H28N4O4 (C29 H28 N4 O4)

Compound Name

2-[4-(4-methoxyphenyl)piperazin-1-yl]-6-(4-methylbenzamido)quinoline-4-carboxylic acid

IUPAC name

2-[4-(4-methoxyphenyl)piperazin-1-yl]-6-(4-methylbenzamido)quinoline-4-carboxylic acid

SMILES

Cc(cc1)ccc1C(Nc(cc1c(C(O)=O)c2)ccc1nc2N(CC1)CCN1c(cc1)ccc1OC)=O

InChI

InChI=1S/C29H28N4O4/c1-19-3-5-20(6-4-19)28(34)30-21-7-12-26-24(17-21)25(29(35)36)18-27(31-26)33-15-13-32(14-16-33)22-8-10-23(37-2)11-9-22/h3-12,17-18H,13-16H2,1-2H3,(H,30,34)(H,35,36)

InChI Key

ODIHLFJUNBCNBP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27187762

Chemical and Physical Properties

Saltdata

3HCl

Molecular Weight

496.57

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

6.112

Distribution Coefficient, logD

3.168

Water Solubility, LogSw

-5.44

Polar Surface Area

73.789

Acid Dissociation Constant (pKa)

4.46

Base Dissociation Constant (pKb)

6.61

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.70

F724-0021 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Protein-Protein Interaction Library (218420 compounds)

RAR (Nuclear receptors) Ligands Library (6524 compounds)

Targeted Diversity Library (40567 compounds)

Epigenetics Focused Set (26518 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Respiratory tract
  • Eye
  • Male
  • Female
  • Hemic and lymphatic
  • Congenital
  • Skin
  • Endocrine
  • Immune system
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Targets:
  • Kinases
  • Nuclear receptors
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with F724-0021 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F724-0021?
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What is the minimum amount of F724-0021 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F724-0021
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F724-0021
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F724-0021 available by request