F724-0082 Screening compound: 6-(4-chlorobenzamido)-2-[4-(2-cyanoethyl)piperazin-1-yl]quinoline-4-carboxylic acid

F724-0082 Screening compound: 6-(4-chlorobenzamido)-2-[4-(2-cyanoethyl)piperazin-1-yl]quinoline-4-carboxylic acid
F724-0082 Screening compound: 6-(4-chlorobenzamido)-2-[4-(2-cyanoethyl)piperazin-1-yl]quinoline-4-carboxylic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound F724-0082
6-(4-chlorobenzamido)-2-[4-(2-cyanoethyl)piperazin-1-yl]quinoline-4-carboxylic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F724-0082

Molecular Formula

C24H22ClN5O3 (C24 H22 ClN5 O3)

Compound Name

6-(4-chlorobenzamido)-2-[4-(2-cyanoethyl)piperazin-1-yl]quinoline-4-carboxylic acid

IUPAC name

6-(4-chlorobenzamido)-2-[4-(2-cyanoethyl)piperazin-1-yl]quinoline-4-carboxylic acid

SMILES

N#CCCN(CC1)CCN1c1cc(C(O)=O)c(cc(cc2)NC(c(cc3)ccc3Cl)=O)c2n1

InChI

InChI=1S/C24H22ClN5O3/c25-17-4-2-16(3-5-17)23(31)27-18-6-7-21-19(14-18)20(24(32)33)15-22(28-21)30-12-10-29(11-13-30)9-1-8-26/h2-7,14-15H,1,9-13H2,(H,27,31)(H,32,33)

InChI Key

RTVXPDPWBZZFRD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14964630

Chemical and Physical Properties

Saltdata

3HCl

Molecular Weight

463.92

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.019

Distribution Coefficient, logD

1.075

Water Solubility, LogSw

-4.46

Polar Surface Area

84.267

Acid Dissociation Constant (pKa)

4.46

Base Dissociation Constant (pKb)

5.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

F724-0082 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Protein-Protein Interaction Library (218420 compounds)

SH2 Library (10483 compounds)

SmartTM Library (51161 compounds)

Antibacterial Compounds Library (13827 compounds)

Epigenetics Focused Set (26518 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Nervous system
  • Cancer
  • Endocrine
  • Infections
  • Immune system
  • animal
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Targets:
  • GPCR
  • Ion Channels
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • Epigenetic

References: we are preparing a list of scientific research reports with F724-0082 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F724-0082?
Check Price and Availability of F724-0082, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F724-0082 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F724-0082
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F724-0082
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F724-0082 available by request