F724-0098 Screening compound: 2-{4-[(dimethylcarbamoyl)methyl]piperazin-1-yl}-6-(4-fluorobenzamido)quinoline-4-carboxylic acid

F724-0098 Screening compound: 2-{4-[(dimethylcarbamoyl)methyl]piperazin-1-yl}-6-(4-fluorobenzamido)quinoline-4-carboxylic acid
F724-0098 Screening compound: 2-{4-[(dimethylcarbamoyl)methyl]piperazin-1-yl}-6-(4-fluorobenzamido)quinoline-4-carboxylic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound F724-0098
2-{4-[(dimethylcarbamoyl)methyl]piperazin-1-yl}-6-(4-fluorobenzamido)quinoline-4-carboxylic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F724-0098

Molecular Formula

C25H26FN5O4 (C25 H26 FN5 O4)

Compound Name

2-{4-[(dimethylcarbamoyl)methyl]piperazin-1-yl}-6-(4-fluorobenzamido)quinoline-4-carboxylic acid

IUPAC name

2-{4-[(dimethylcarbamoyl)methyl]piperazin-1-yl}-6-(4-fluorobenzamido)quinoline-4-carboxylic acid

SMILES

CN(C)C(CN(CC1)CCN1c1cc(C(O)=O)c(cc(cc2)NC(c(cc3)ccc3F)=O)c2n1)=O

InChI

InChI=1S/C25H26FN5O4/c1-29(2)23(32)15-30-9-11-31(12-10-30)22-14-20(25(34)35)19-13-18(7-8-21(19)28-22)27-24(33)16-3-5-17(26)6-4-16/h3-8,13-14H,9-12,15H2,1-2H3,(H,27,33)(H,34,35)

InChI Key

ACLMOFVTCJIPFN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27187803

Chemical and Physical Properties

Saltdata

3HCl

Molecular Weight

479.51

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.695

Distribution Coefficient, logD

-0.249

Water Solubility, LogSw

-3.13

Polar Surface Area

82.270

Acid Dissociation Constant (pKa)

4.46

Base Dissociation Constant (pKb)

5.21

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.00

F724-0098 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Protein-Protein Interaction Library (218420 compounds)

SH2 Library (10483 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with F724-0098 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F724-0098?
Check Price and Availability of F724-0098, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F724-0098 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F724-0098
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F724-0098
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F724-0098 available by request