F724-0345 Screening compound: 2-[4-(ethoxycarbonyl)piperazin-1-yl]-6-propanamidoquinoline-4-carboxylic acid

F724-0345 Screening compound: 2-[4-(ethoxycarbonyl)piperazin-1-yl]-6-propanamidoquinoline-4-carboxylic acid
F724-0345 Screening compound: 2-[4-(ethoxycarbonyl)piperazin-1-yl]-6-propanamidoquinoline-4-carboxylic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound F724-0345
2-[4-(ethoxycarbonyl)piperazin-1-yl]-6-propanamidoquinoline-4-carboxylic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F724-0345

Molecular Formula

C20H24N4O5 (C20 H24 N4 O5)

Compound Name

2-[4-(ethoxycarbonyl)piperazin-1-yl]-6-propanamidoquinoline-4-carboxylic acid

IUPAC name

2-[4-(ethoxycarbonyl)piperazin-1-yl]-6-propanamidoquinoline-4-carboxylic acid

SMILES

CCC(Nc(cc1c(C(O)=O)c2)ccc1nc2N(CC1)CCN1C(OCC)=O)=O

InChI

InChI=1S/C20H24N4O5/c1-3-18(25)21-13-5-6-16-14(11-13)15(19(26)27)12-17(22-16)23-7-9-24(10-8-23)20(28)29-4-2/h5-6,11-12H,3-4,7-10H2,1-2H3,(H,21,25)(H,26,27)

InChI Key

VHLKCOVJYFIYGP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14964675

Chemical and Physical Properties

Saltdata

3HCl

Molecular Weight

400.43

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.365

Distribution Coefficient, logD

0.421

Water Solubility, LogSw

-3.44

Polar Surface Area

85.823

Acid Dissociation Constant (pKa)

4.46

Base Dissociation Constant (pKb)

3.60

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

F724-0345 in Drug Discovery

Included in Screening Libraries

Eccentric PPI Library (11937 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular

References: we are preparing a list of scientific research reports with F724-0345 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F724-0345?
Check Price and Availability of F724-0345, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F724-0345 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F724-0345
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F724-0345
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F724-0345 available by request