F724-0645 Screening compound: 6-[(cyclobutylcarbonyl)amino]-2-(4-{2-[(2-methoxyethyl)amino]-2-oxoethyl}piperazino)-4-quinolinecarboxylic acid

F724-0645 Screening compound: 6-[(cyclobutylcarbonyl)amino]-2-(4-{2-[(2-methoxyethyl)amino]-2-oxoethyl}piperazino)-4-quinolinecarboxylic acid
F724-0645 Screening compound: 6-[(cyclobutylcarbonyl)amino]-2-(4-{2-[(2-methoxyethyl)amino]-2-oxoethyl}piperazino)-4-quinolinecarboxylic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound F724-0645
6-[(cyclobutylcarbonyl)amino]-2-(4-{2-[(2-methoxyethyl)amino]-2-oxoethyl}piperazino)-4-quinolinecarboxylic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F724-0645

Molecular Formula

C24H31N5O5 (C24 H31 N5 O5)

Compound Name

6-[(cyclobutylcarbonyl)amino]-2-(4-{2-[(2-methoxyethyl)amino]-2-oxoethyl}piperazino)-4-quinolinecarboxylic acid

IUPAC name

6-cyclobutaneamido-2-(4-{[(2-methoxyethyl)carbamoyl]methyl}piperazin-1-yl)quinoline-4-carboxylic acid

SMILES

COCCNC(CN(CC1)CCN1c(cc(C(O)=O)c1c2)nc1ccc2NC(C1CCC1)=O)=O

InChI

InChI=1S/C24H31N5O5/c1-34-12-7-25-22(30)15-28-8-10-29(11-9-28)21-14-19(24(32)33)18-13-17(5-6-20(18)27-21)26-23(31)16-3-2-4-16/h5-6,13-14,16H,2-4,7-12,15H2,1H3,(H,25,30)(H,26,31)(H,32,33)

InChI Key

NGNHRYQFPIUMRA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27188031

Chemical and Physical Properties

Saltdata

3HCl

Molecular Weight

469.54

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

1.872

Distribution Coefficient, logD

-1.072

Water Solubility, LogSw

-2.72

Polar Surface Area

99.975

Acid Dissociation Constant (pKa)

4.46

Base Dissociation Constant (pKb)

5.41

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

F724-0645 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Epigenetics Focused Set (26518 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with F724-0645 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F724-0645?
Check Price and Availability of F724-0645, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F724-0645 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F724-0645
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F724-0645
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F724-0645 available by request