F725-0370 Screening compound: N-cyclohexyl-3-{[6-(4-fluorophenyl)pyrimidin-4-yl]amino}-N-methylbenzamide

F725-0370 Screening compound: N-cyclohexyl-3-{[6-(4-fluorophenyl)pyrimidin-4-yl]amino}-N-methylbenzamide
F725-0370 Screening compound: N-cyclohexyl-3-{[6-(4-fluorophenyl)pyrimidin-4-yl]amino}-N-methylbenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F725-0370
N-cyclohexyl-3-{[6-(4-fluorophenyl)pyrimidin-4-yl]amino}-N-methylbenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F725-0370

Molecular Formula

C24H25FN4O (C24 H25 FN4 O)

Compound Name

N-cyclohexyl-3-{[6-(4-fluorophenyl)pyrimidin-4-yl]amino}-N-methylbenzamide

IUPAC name

N-cyclohexyl-3-{[6-(4-fluorophenyl)pyrimidin-4-yl]amino}-N-methylbenzamide

SMILES

CN(C1CCCCC1)C(c1cccc(Nc2cc(-c(cc3)ccc3F)ncn2)c1)=O

InChI

InChI=1S/C24H25FN4O/c1-29(21-8-3-2-4-9-21)24(30)18-6-5-7-20(14-18)28-23-15-22(26-16-27-23)17-10-12-19(25)13-11-17/h5-7,10-16,21H,2-4,8-9H2,1H3,(H,26,27,28)

InChI Key

VOWVWXUEKMHPPP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14964816

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

404.49

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.528

Distribution Coefficient, logD

5.497

Water Solubility, LogSw

-5.39

Polar Surface Area

44.458

Acid Dissociation Constant (pKa)

19.62

Base Dissociation Constant (pKb)

6.27

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.20

F725-0370 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS BBB Library (22607 compounds)

CNS Targets (44014 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Antiviral
  • Infections
  • Immune system
  • Nervous system
  • Nervous system
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with F725-0370 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F725-0370?
Check Price and Availability of F725-0370, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F725-0370 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F725-0370
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F725-0370
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F725-0370 available by request