F726-0372 Screening compound: N-(3,5-difluorophenyl)-1-[2-(4-fluorophenyl)pyrimidin-4-yl]piperidine-3-carboxamide

F726-0372 Screening compound: N-(3,5-difluorophenyl)-1-[2-(4-fluorophenyl)pyrimidin-4-yl]piperidine-3-carboxamide
F726-0372 Screening compound: N-(3,5-difluorophenyl)-1-[2-(4-fluorophenyl)pyrimidin-4-yl]piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F726-0372
N-(3,5-difluorophenyl)-1-[2-(4-fluorophenyl)pyrimidin-4-yl]piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F726-0372

Molecular Formula

C22H19F3N4O (C22 H19 F3 N4 O)

Compound Name

N-(3,5-difluorophenyl)-1-[2-(4-fluorophenyl)pyrimidin-4-yl]piperidine-3-carboxamide

IUPAC name

N-(35-difluorophenyl)-1-[2-(4-fluorophenyl)pyrimidin-4-yl]piperidine-3-carboxamide

SMILES

O=C(C(CCC1)CN1c1nc(-c(cc2)ccc2F)ncc1)Nc1cc(F)cc(F)c1

InChI

InChI=1S/C22H19F3N4O/c23-16-5-3-14(4-6-16)21-26-8-7-20(28-21)29-9-1-2-15(13-29)22(30)27-19-11-17(24)10-18(25)12-19/h3-8,10-12,15H,1-2,9,13H2,(H,27,30)/t15-/m0/s1

InChI Key

YKJYIXRSOVLWQT-HNNXBMFYSA-N

MDL Number (MFCD)

MFCD27188296

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

412.41

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.472

Distribution Coefficient, logD

4.393

Water Solubility, LogSw

-4.35

Polar Surface Area

44.911

Acid Dissociation Constant (pKa)

8.11

Base Dissociation Constant (pKb)

4.84

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

22.70

F726-0372 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with F726-0372 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F726-0372?
Check Price and Availability of F726-0372, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F726-0372 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F726-0372
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F726-0372
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F726-0372 available by request