F735-0247 Screening compound: N-{4-[4-(3-chlorophenyl)piperazine-1-carbonyl]phenyl}-5-methyl-1,3,4-thiadiazole-2-carboxamide

F735-0247 Screening compound: N-{4-[4-(3-chlorophenyl)piperazine-1-carbonyl]phenyl}-5-methyl-1,3,4-thiadiazole-2-carboxamide
F735-0247 Screening compound: N-{4-[4-(3-chlorophenyl)piperazine-1-carbonyl]phenyl}-5-methyl-1,3,4-thiadiazole-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F735-0247
N-{4-[4-(3-chlorophenyl)piperazine-1-carbonyl]phenyl}-5-methyl-1,3,4-thiadiazole-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F735-0247

Molecular Formula

C21H20ClN5O2S (C21 H20 ClN5 O2 S)

Compound Name

N-{4-[4-(3-chlorophenyl)piperazine-1-carbonyl]phenyl}-5-methyl-1,3,4-thiadiazole-2-carboxamide

IUPAC name

N-{4-[4-(3-chlorophenyl)piperazine-1-carbonyl]phenyl}-5-methyl-134-thiadiazole-2-carboxamide

SMILES

Cc1nnc(C(Nc(cc2)ccc2C(N(CC2)CCN2c2cccc(Cl)c2)=O)=O)s1

InChI

InChI=1S/C21H20ClN5O2S/c1-14-24-25-20(30-14)19(28)23-17-7-5-15(6-8-17)21(29)27-11-9-26(10-12-27)18-4-2-3-16(22)13-18/h2-8,13H,9-12H2,1H3,(H,23,28)

InChI Key

DGDPRPKHHVZQQX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14965196

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

441.94

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.807

Distribution Coefficient, logD

2.800

Water Solubility, LogSw

-3.72

Polar Surface Area

66.549

Acid Dissociation Constant (pKa)

9.21

Base Dissociation Constant (pKb)

4.64

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.80

F735-0247 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with F735-0247 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F735-0247?
Check Price and Availability of F735-0247, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F735-0247 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F735-0247
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F735-0247
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F735-0247 available by request