F743-0221 Screening compound: N-(1-benzyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)-5,6,7,8-tetrahydronaphthalene-2-sulfonamide

F743-0221 Screening compound: N-(1-benzyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)-5,6,7,8-tetrahydronaphthalene-2-sulfonamide
F743-0221 Screening compound: N-(1-benzyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)-5,6,7,8-tetrahydronaphthalene-2-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F743-0221
N-(1-benzyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)-5,6,7,8-tetrahydronaphthalene-2-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F743-0221

Molecular Formula

C26H26N2O3S (C26 H26 N2 O3 S)

Compound Name

N-(1-benzyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)-5,6,7,8-tetrahydronaphthalene-2-sulfonamide

IUPAC name

N-(1-benzyl-2-oxo-1234-tetrahydroquinolin-6-yl)-5678-tetrahydronaphthalene-2-sulfonamide

SMILES

O=C(CC1)N(Cc2ccccc2)c(cc2)c1cc2NS(c1cc(CCCC2)c2cc1)(=O)=O

InChI

InChI=1S/C26H26N2O3S/c29-26-15-11-22-16-23(12-14-25(22)28(26)18-19-6-2-1-3-7-19)27-32(30,31)24-13-10-20-8-4-5-9-21(20)17-24/h1-3,6-7,10,12-14,16-17,27H,4-5,8-9,11,15,18H2

InChI Key

PQRYTLAJSIHMDO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09245270

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

446.57

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.769

Distribution Coefficient, logD

5.738

Water Solubility, LogSw

-5.78

Polar Surface Area

56.189

Acid Dissociation Constant (pKa)

8.53

Base Dissociation Constant (pKb)

-1.69

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.90

F743-0221 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F743-0221 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F743-0221?
Check Price and Availability of F743-0221, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F743-0221 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F743-0221
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F743-0221
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F743-0221 available by request