F755-0114 Screening compound: 5-[(5-{[4-(2-pyrimidinyl)piperazino]carbonyl}-2-furyl)methyl]pyrido[2,3-e]pyrrolo[1,2-a]pyrazin-6(5H)-one

F755-0114 Screening compound: 5-[(5-{[4-(2-pyrimidinyl)piperazino]carbonyl}-2-furyl)methyl]pyrido[2,3-e]pyrrolo[1,2-a]pyrazin-6(5H)-one
F755-0114 Screening compound: 5-[(5-{[4-(2-pyrimidinyl)piperazino]carbonyl}-2-furyl)methyl]pyrido[2,3-e]pyrrolo[1,2-a]pyrazin-6(5H)-one alternative view

Chemical Structure Depiction of ChemDiv screening compound F755-0114
5-[(5-{[4-(2-pyrimidinyl)piperazino]carbonyl}-2-furyl)methyl]pyrido[2,3-e]pyrrolo[1,2-a]pyrazin-6(5H)-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F755-0114

Molecular Formula

C24H21N7O3 (C24 H21 N7 O3)

Compound Name

5-[(5-{[4-(2-pyrimidinyl)piperazino]carbonyl}-2-furyl)methyl]pyrido[2,3-e]pyrrolo[1,2-a]pyrazin-6(5H)-one

IUPAC name

8-({5-[4-(pyrimidin-2-yl)piperazine-1-carbonyl]furan-2-yl}methyl)-2810-triazatricyclo[7.4.0.0^{26}]trideca-1(13)35911-pentaen-7-one

SMILES

O=C(c1ccc(CN(C2=O)c3ncccc3-n3c2ccc3)o1)N(CC1)CCN1c1ncccn1

InChI

InChI=1S/C24H21N7O3/c32-22-19-5-2-11-30(19)18-4-1-8-25-21(18)31(22)16-17-6-7-20(34-17)23(33)28-12-14-29(15-13-28)24-26-9-3-10-27-24/h1-11H,12-16H2

InChI Key

GQNPEWQIRCXHJS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27189170

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

455.48

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.788

Distribution Coefficient, logD

2.788

Water Solubility, LogSw

-2.98

Polar Surface Area

73.409

Acid Dissociation Constant (pKa)

21.08

Base Dissociation Constant (pKb)

2.67

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.80

F755-0114 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F755-0114 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F755-0114?
Check Price and Availability of F755-0114, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F755-0114 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F755-0114
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F755-0114
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F755-0114 available by request