F783-0307 Screening compound: 2-[(4-acetamidophenyl)methyl]-N-[(4-fluorophenyl)methyl]-1H-1,3-benzodiazole-5-carboxamide

Chemical Structure Depiction of ChemDiv screening compound F783-0307
2-[(4-acetamidophenyl)methyl]-N-[(4-fluorophenyl)methyl]-1H-1,3-benzodiazole-5-carboxamide

Available from 1 mg

Formats:

Glass Vials (4ml Glass Vials VWR #97047-678)
96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Check Price and Availability

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F783-0307

Molecular Formula

C₂₄H₂₁FN₄O₂ (C24 H21 FN4 O2)

Compound Name

2-[(4-acetamidophenyl)methyl]-N-[(4-fluorophenyl)methyl]-1H-1,3-benzodiazole-5-carboxamide

IUPAC name

2-[(4-acetamidophenyl)methyl]-N-[(4-fluorophenyl)methyl]-1H-13-benzodiazole-5-carboxamide

SMILES

CC(Nc1ccc(Cc2nc(cc(cc3)C(NCc(cc4)ccc4F)=O)c3[nH]2)cc1)=O

InChI

InChI=1S/C24H21FN4O2/c1-15(30)27-20-9-4-16(5-10-20)12-23-28-21-11-6-18(13-22(21)29-23)24(31)26-14-17-2-7-19(25)8-3-17/h2-11,13H,12,14H2,1H3,(H,26,31)(H,27,30)(H,28,29)

InChI Key

YUJMRFSCKLQTDF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14966713

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

416.45

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

Partition Coefficient, logP

3.543

Distribution Coefficient, logD

3.542

Water Solubility, LogSw

-3.79

Polar Surface Area

67.924

Acid Dissociation Constant (pK_a)

10.78

Base Dissociation Constant (pK_b)

4.89

Number of Chiral Centers

0.00

Percent sp³ carbon bonding

12.50

F783-0307 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

CORONAVIRUS Library (20774 compounds)

Integrin Receptors Targeted library (1715 compounds)

KRAS-Targeted Library (16000 compounds)

PLpro Library (6343 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Structure:

Therapeutical areas:

Antiviral
Infections
Immune system
Cancer
Musculoskeletal
Digestive system
Nervous system
Hemic and lymphatic
Cardiovascular
Immune system
Cancer
Digestive system
Respiratory tract
Otorhinolaryngologic
Antiviral
Infections
Immune system
Infections
Cancer
Musculoskeletal
Digestive system
Respiratory tract
Male
Female
Cardiovascular
Skin
Metabolic
Immune system
Immune system

Targets:

Others
Kinases
Proteases

Mechanism of action:

PPI modulators
Receptor's ligands

References: we are preparing a list of scientific research reports with F783-0307 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F783-0307?
Check Price and Availability of F783-0307, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.

What is the minimum amount of F783-0307 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.

Delivery options for F783-0307
ChemDiv sends parcels with Express services (UPS, WC).

1–2 days for small orders
2–4 weeks for large selections

Delivery formats for F783-0307

0.5–50 mg of dry powder sample in single glass vials, custom vials
DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F783-0307 available by request