F792-1284 Screening compound: N-(3-chlorophenyl)-5-[1-(4-methylbenzoyl)pyrrolidin-2-yl]-1,3,4-thiadiazole-2-carboxamide

F792-1284 Screening compound: N-(3-chlorophenyl)-5-[1-(4-methylbenzoyl)pyrrolidin-2-yl]-1,3,4-thiadiazole-2-carboxamide
F792-1284 Screening compound: N-(3-chlorophenyl)-5-[1-(4-methylbenzoyl)pyrrolidin-2-yl]-1,3,4-thiadiazole-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F792-1284
N-(3-chlorophenyl)-5-[1-(4-methylbenzoyl)pyrrolidin-2-yl]-1,3,4-thiadiazole-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F792-1284

Molecular Formula

C21H19ClN4O2S (C21 H19 ClN4 O2 S)

Compound Name

N-(3-chlorophenyl)-5-[1-(4-methylbenzoyl)pyrrolidin-2-yl]-1,3,4-thiadiazole-2-carboxamide

IUPAC name

N-(3-chlorophenyl)-5-[1-(4-methylbenzoyl)pyrrolidin-2-yl]-134-thiadiazole-2-carboxamide

SMILES

Cc(cc1)ccc1C(N(CCC1)C1c1nnc(C(Nc2cccc(Cl)c2)=O)s1)=O

InChI

InChI=1S/C21H19ClN4O2S/c1-13-7-9-14(10-8-13)21(28)26-11-3-6-17(26)19-24-25-20(29-19)18(27)23-16-5-2-4-15(22)12-16/h2,4-5,7-10,12,17H,3,6,11H2,1H3,(H,23,27)/t17-/m0/s1

InChI Key

PLBGZRADMFEMFZ-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD27190169

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

426.93

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.170

Distribution Coefficient, logD

4.167

Water Solubility, LogSw

-4.42

Polar Surface Area

63.270

Acid Dissociation Constant (pKa)

9.52

Base Dissociation Constant (pKb)

-1.95

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

23.80

F792-1284 in Drug Discovery

Included in Screening Libraries

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with F792-1284 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F792-1284?
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What is the minimum amount of F792-1284 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F792-1284
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F792-1284
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F792-1284 available by request