F810-0465 Screening compound: N-(2H-1,3-benzodioxol-5-yl)-2-{8-fluoro-3-oxo-2H,3H-[1,2,4]triazolo[4,3-c]quinazolin-2-yl}acetamide

F810-0465 Screening compound: N-(2H-1,3-benzodioxol-5-yl)-2-{8-fluoro-3-oxo-2H,3H-[1,2,4]triazolo[4,3-c]quinazolin-2-yl}acetamide
F810-0465 Screening compound: N-(2H-1,3-benzodioxol-5-yl)-2-{8-fluoro-3-oxo-2H,3H-[1,2,4]triazolo[4,3-c]quinazolin-2-yl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F810-0465
N-(2H-1,3-benzodioxol-5-yl)-2-{8-fluoro-3-oxo-2H,3H-[1,2,4]triazolo[4,3-c]quinazolin-2-yl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F810-0465

Molecular Formula

C18H12FN5O4 (C18 H12 FN5 O4)

Compound Name

N-(2H-1,3-benzodioxol-5-yl)-2-{8-fluoro-3-oxo-2H,3H-[1,2,4]triazolo[4,3-c]quinazolin-2-yl}acetamide

IUPAC name

N-(2H-13-benzodioxol-5-yl)-2-{8-fluoro-3-oxo-2H3H-[124]triazolo[43-c]quinazolin-2-yl}acetamide

SMILES

O=C(CN1N=C(c(ccc(F)c2)c2N=C2)N2C1=O)Nc(cc1)cc2c1OCO2

InChI

InChI=1S/C18H12FN5O4/c19-10-1-3-12-13(5-10)20-8-23-17(12)22-24(18(23)26)7-16(25)21-11-2-4-14-15(6-11)28-9-27-14/h1-6,8H,7,9H2,(H,21,25)

InChI Key

NVGDXTQXAZTLRW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27193061

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

381.32

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.140

Distribution Coefficient, logD

2.140

Water Solubility, LogSw

-3.17

Polar Surface Area

81.952

Acid Dissociation Constant (pKa)

12.03

Base Dissociation Constant (pKb)

2.94

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.10

F810-0465 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Angiogenesis library (14822 compounds)

Anti-Inflammatory Library (24602 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • Kinases
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F810-0465 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F810-0465?
Check Price and Availability of F810-0465, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F810-0465 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F810-0465
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F810-0465
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F810-0465 available by request