F825-1678 Screening compound: 1-(1-{[5-(1H-pyrazol-5-yl)furan-2-yl]sulfonyl}piperidine-3-carbonyl)-4-(pyridin-2-yl)piperazine

F825-1678 Screening compound: 1-(1-{[5-(1H-pyrazol-5-yl)furan-2-yl]sulfonyl}piperidine-3-carbonyl)-4-(pyridin-2-yl)piperazine
F825-1678 Screening compound: 1-(1-{[5-(1H-pyrazol-5-yl)furan-2-yl]sulfonyl}piperidine-3-carbonyl)-4-(pyridin-2-yl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound F825-1678
1-(1-{[5-(1H-pyrazol-5-yl)furan-2-yl]sulfonyl}piperidine-3-carbonyl)-4-(pyridin-2-yl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F825-1678

Molecular Formula

C22H26N6O4S (C22 H26 N6 O4 S)

Compound Name

1-(1-{[5-(1H-pyrazol-5-yl)furan-2-yl]sulfonyl}piperidine-3-carbonyl)-4-(pyridin-2-yl)piperazine

IUPAC name

1-(1-{[5-(1H-pyrazol-5-yl)furan-2-yl]sulfonyl}piperidine-3-carbonyl)-4-(pyridin-2-yl)piperazine

SMILES

O=C(C(CCC1)CN1S(c1ccc(-c2ccn[nH]2)o1)(=O)=O)N(CC1)CCN1c1ncccc1

InChI

InChI=1S/C22H26N6O4S/c29-22(27-14-12-26(13-15-27)20-5-1-2-9-23-20)17-4-3-11-28(16-17)33(30,31)21-7-6-19(32-21)18-8-10-24-25-18/h1-2,5-10,17H,3-4,11-16H2,(H,24,25)/t17-/m0/s1

InChI Key

PKDXOMIHPHGZIQ-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD27196094

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

470.55

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.118

Distribution Coefficient, logD

2.109

Water Solubility, LogSw

-2.56

Polar Surface Area

92.524

Acid Dissociation Constant (pKa)

12.93

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

40.90

F825-1678 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

SmartTM Library (51161 compounds)

Akt-Targeted Library (14764 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F825-1678 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F825-1678?
Check Price and Availability of F825-1678, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F825-1678 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F825-1678
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F825-1678
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F825-1678 available by request