F836-0767 Screening compound: 3-{[4-(2-chlorophenyl)piperazin-1-yl]sulfonyl}-N-[(pyridin-2-yl)methyl]thiophene-2-carboxamide

F836-0767 Screening compound: 3-{[4-(2-chlorophenyl)piperazin-1-yl]sulfonyl}-N-[(pyridin-2-yl)methyl]thiophene-2-carboxamide
F836-0767 Screening compound: 3-{[4-(2-chlorophenyl)piperazin-1-yl]sulfonyl}-N-[(pyridin-2-yl)methyl]thiophene-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F836-0767
3-{[4-(2-chlorophenyl)piperazin-1-yl]sulfonyl}-N-[(pyridin-2-yl)methyl]thiophene-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F836-0767

Molecular Formula

C21H21ClN4O3S2 (C21 H21 ClN4 O3 S2)

Compound Name

3-{[4-(2-chlorophenyl)piperazin-1-yl]sulfonyl}-N-[(pyridin-2-yl)methyl]thiophene-2-carboxamide

IUPAC name

3-{[4-(2-chlorophenyl)piperazin-1-yl]sulfonyl}-N-[(pyridin-2-yl)methyl]thiophene-2-carboxamide

SMILES

O=C(c(scc1)c1S(N(CC1)CCN1c(cccc1)c1Cl)(=O)=O)NCc1ncccc1

InChI

InChI=1S/C21H21ClN4O3S2/c22-17-6-1-2-7-18(17)25-10-12-26(13-11-25)31(28,29)19-8-14-30-20(19)21(27)24-15-16-5-3-4-9-23-16/h1-9,14H,10-13,15H2,(H,24,27)

InChI Key

GONOQJKEEDJKFY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27198237

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

477.01

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.217

Distribution Coefficient, logD

3.216

Water Solubility, LogSw

-3.45

Polar Surface Area

69.884

Acid Dissociation Constant (pKa)

11.05

Base Dissociation Constant (pKb)

3.56

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.80

F836-0767 in Drug Discovery

Included in Screening Libraries

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with F836-0767 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F836-0767?
Check Price and Availability of F836-0767, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F836-0767 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F836-0767
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F836-0767
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F836-0767 available by request