F853-0129 Screening compound: 1-[6-(2,5-dimethoxybenzenesulfonyl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]piperidine

F853-0129 Screening compound: 1-[6-(2,5-dimethoxybenzenesulfonyl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]piperidine
F853-0129 Screening compound: 1-[6-(2,5-dimethoxybenzenesulfonyl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound F853-0129
1-[6-(2,5-dimethoxybenzenesulfonyl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F853-0129

Molecular Formula

C20H26N4O4S (C20 H26 N4 O4 S)

Compound Name

1-[6-(2,5-dimethoxybenzenesulfonyl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]piperidine

IUPAC name

1-[6-(25-dimethoxybenzenesulfonyl)-5H6H7H8H-pyrido[43-d]pyrimidin-2-yl]piperidine

SMILES

COc(cc1)cc(S(N(CC2)Cc3c2nc(N2CCCCC2)nc3)(=O)=O)c1OC

InChI

InChI=1S/C20H26N4O4S/c1-27-16-6-7-18(28-2)19(12-16)29(25,26)24-11-8-17-15(14-24)13-21-20(22-17)23-9-4-3-5-10-23/h6-7,12-13H,3-5,8-11,14H2,1-2H3

InChI Key

YFUODBSFBFIKCG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27200007

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

418.52

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.622

Distribution Coefficient, logD

2.620

Water Solubility, LogSw

-2.89

Polar Surface Area

69.759

Acid Dissociation Constant (pKa)

20.31

Base Dissociation Constant (pKb)

4.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

F853-0129 in Drug Discovery

Included in Screening Libraries

CNS MPO Library (28609 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with F853-0129 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F853-0129?
Check Price and Availability of F853-0129, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F853-0129 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F853-0129
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F853-0129
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F853-0129 available by request