F853-0131 Screening compound: 1-[6-(thiophene-2-sulfonyl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]piperidine

F853-0131 Screening compound: 1-[6-(thiophene-2-sulfonyl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]piperidine
F853-0131 Screening compound: 1-[6-(thiophene-2-sulfonyl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound F853-0131
1-[6-(thiophene-2-sulfonyl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F853-0131

Molecular Formula

C16H20N4O2S2 (C16 H20 N4 O2 S2)

Compound Name

1-[6-(thiophene-2-sulfonyl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]piperidine

IUPAC name

1-[6-(thiophene-2-sulfonyl)-5H6H7H8H-pyrido[43-d]pyrimidin-2-yl]piperidine

SMILES

O=S(c1cccs1)(N(CC1)Cc2c1nc(N1CCCCC1)nc2)=O

InChI

InChI=1S/C16H20N4O2S2/c21-24(22,15-5-4-10-23-15)20-9-6-14-13(12-20)11-17-16(18-14)19-7-2-1-3-8-19/h4-5,10-11H,1-3,6-9,12H2

InChI Key

DFTSTYIGHXPARR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14967776

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

364.49

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.407

Distribution Coefficient, logD

2.406

Water Solubility, LogSw

-2.55

Polar Surface Area

55.603

Acid Dissociation Constant (pKa)

20.48

Base Dissociation Constant (pKb)

4.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

F853-0131 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS MPO Library (28609 compounds)

GPCR Targeted Library (31838 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • GPCR
  • Others
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with F853-0131 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F853-0131?
Check Price and Availability of F853-0131, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F853-0131 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F853-0131
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F853-0131
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F853-0131 available by request