F865-0327 Screening compound: N-(4-methylphenyl)-5-[4-({[3-(pyrrolidin-1-yl)butyl]carbamoyl}methyl)piperidine-1-carbonyl]-1,3,4-thiadiazole-2-carboxamide

F865-0327 Screening compound: N-(4-methylphenyl)-5-[4-({[3-(pyrrolidin-1-yl)butyl]carbamoyl}methyl)piperidine-1-carbonyl]-1,3,4-thiadiazole-2-carboxamide
F865-0327 Screening compound: N-(4-methylphenyl)-5-[4-({[3-(pyrrolidin-1-yl)butyl]carbamoyl}methyl)piperidine-1-carbonyl]-1,3,4-thiadiazole-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F865-0327
N-(4-methylphenyl)-5-[4-({[3-(pyrrolidin-1-yl)butyl]carbamoyl}methyl)piperidine-1-carbonyl]-1,3,4-thiadiazole-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F865-0327

Molecular Formula

C26H36N6O3S (C26 H36 N6 O3 S)

Compound Name

N-(4-methylphenyl)-5-[4-({[3-(pyrrolidin-1-yl)butyl]carbamoyl}methyl)piperidine-1-carbonyl]-1,3,4-thiadiazole-2-carboxamide

IUPAC name

N-(4-methylphenyl)-5-[4-({[3-(pyrrolidin-1-yl)butyl]carbamoyl}methyl)piperidine-1-carbonyl]-134-thiadiazole-2-carboxamide

SMILES

CC(CCNC(CC(CC1)CCN1C(c1nnc(C(Nc2ccc(C)cc2)=O)s1)=O)=O)N1CCCC1

InChI

InChI=1S/C26H36N6O3S/c1-18-5-7-21(8-6-18)28-23(34)24-29-30-25(36-24)26(35)32-15-10-20(11-16-32)17-22(33)27-12-9-19(2)31-13-3-4-14-31/h5-8,19-20H,3-4,9-17H2,1-2H3,(H,27,33)(H,28,34)/t19-/m0/s1

InChI Key

FJNXBWQYJZZREA-IBGZPJMESA-N

MDL Number (MFCD)

MFCD14968919

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

512.68

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

12.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.367

Distribution Coefficient, logD

-1.086

Water Solubility, LogSw

-2.96

Polar Surface Area

91.530

Acid Dissociation Constant (pKa)

10.04

Base Dissociation Constant (pKb)

10.85

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

57.70

F865-0327 in Drug Discovery

Included in Screening Libraries

Antiviral HBV Library (10007 compounds)

Antiviral Library (67538 compounds)

GPCR Targeted Library (31838 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • GPCR
  • Phosphatases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F865-0327 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F865-0327?
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What is the minimum amount of F865-0327 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F865-0327
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F865-0327
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F865-0327 available by request