F869-0361 Screening compound: 1-[2-(4-fluorophenyl)-4-pyrimidinyl]-N~4~-(4-morpholinophenyl)-4-piperidinecarboxamide

F869-0361 Screening compound: 1-[2-(4-fluorophenyl)-4-pyrimidinyl]-N~4~-(4-morpholinophenyl)-4-piperidinecarboxamide
F869-0361 Screening compound: 1-[2-(4-fluorophenyl)-4-pyrimidinyl]-N~4~-(4-morpholinophenyl)-4-piperidinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F869-0361
1-[2-(4-fluorophenyl)-4-pyrimidinyl]-N~4~-(4-morpholinophenyl)-4-piperidinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F869-0361

Molecular Formula

C26H28FN5O2 (C26 H28 FN5 O2)

Compound Name

1-[2-(4-fluorophenyl)-4-pyrimidinyl]-N~4~-(4-morpholinophenyl)-4-piperidinecarboxamide

IUPAC name

1-[2-(4-fluorophenyl)pyrimidin-4-yl]-N-[4-(morpholin-4-yl)phenyl]piperidine-4-carboxamide

SMILES

O=C(C(CC1)CCN1c1ccnc(-c(cc2)ccc2F)n1)Nc(cc1)ccc1N1CCOCC1

InChI

InChI=1S/C26H28FN5O2/c27-21-3-1-19(2-4-21)25-28-12-9-24(30-25)32-13-10-20(11-14-32)26(33)29-22-5-7-23(8-6-22)31-15-17-34-18-16-31/h1-9,12,20H,10-11,13-18H2,(H,29,33)

InChI Key

YDKGXYCSAITAGJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27200699

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

461.54

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.851

Distribution Coefficient, logD

3.849

Water Solubility, LogSw

-4.09

Polar Surface Area

56.338

Acid Dissociation Constant (pKa)

11.90

Base Dissociation Constant (pKb)

4.84

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.62

F869-0361 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

PI3K-Targeted Library (17255 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F869-0361 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F869-0361?
Check Price and Availability of F869-0361, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F869-0361 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F869-0361
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F869-0361
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F869-0361 available by request