F869-0361 Screening compound: 1-[2-(4-fluorophenyl)-4-pyrimidinyl]-N~4~-(4-morpholinophenyl)-4-piperidinecarboxamide
Chemical Structure Depiction of ChemDiv screening compound F869-0361
1-[2-(4-fluorophenyl)-4-pyrimidinyl]-N~4~-(4-morpholinophenyl)-4-piperidinecarboxamide
Available from 1 mg
Formats:
- Glass Vials (4ml Glass Vials VWR #97047-678)
- 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)
Shiptime: 1 week worldwide delivery in most cases
Compound Identifiers
ChemDiv Compound ID
F869-0361
Molecular Formula
C26H28FN5O2 (C26 H28 FN5 O2)
Compound Name
1-[2-(4-fluorophenyl)-4-pyrimidinyl]-N~4~-(4-morpholinophenyl)-4-piperidinecarboxamide
IUPAC name
1-[2-(4-fluorophenyl)pyrimidin-4-yl]-N-[4-(morpholin-4-yl)phenyl]piperidine-4-carboxamide
SMILES
O=C(C(CC1)CCN1c1ccnc(-c(cc2)ccc2F)n1)Nc(cc1)ccc1N1CCOCC1
InChI Key
MDL Number (MFCD)
Chemical and Physical Properties
Saltdata
n/a
Molecular Weight
461.54
Hydrogen Bond Acceptors Count
5.00
Hydrogen Bond Donors Count
1.00
Rotatable Bond Count
6.00
Number of Nitrogen and Oxygen Atoms
7
Partition Coefficient, logP
3.851
Distribution Coefficient, logD
3.849
Water Solubility, LogSw
-4.09
Polar Surface Area
56.338
Acid Dissociation Constant (pKa)
11.90
Base Dissociation Constant (pKb)
4.84
Number of Chiral Centers
0.00
Percent sp3 carbon bonding
34.62
F869-0361 in Drug Discovery
Included in Screening Libraries
300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)
GPCR Targeted Library (31838 compounds)
Macl-GPIb alpha Interaction Library (22969 compounds)
PI3K-Targeted Library (17255 compounds)
Targeted Diversity Library (40567 compounds)
Akt-Targeted Library (14764 compounds)
Included in 1.7M Stock Database
- Musculoskeletal
- Respiratory tract
- Nervous system
- Congenital
- Skin
- Metabolic
- Endocrine
- Hemic and lymphatic
- Cardiovascular
- Cancer
- Digestive system
- Respiratory tract
- Otorhinolaryngologic
- Male
- Female
- Hemic and lymphatic
- Skin
- Digestive system
- Respiratory tract
- Male
- Female
- Hemic and lymphatic
- Skin
- GPCR
- Kinases
- Kinases
- Receptor's ligands
References: we are preparing a list of scientific research reports with F869-0361 chemical compound. It will be published here after verification.
Frequently Asked Questions
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Available from 1 mg in Glass Vials or 96-tube racks.
ChemDiv sends parcels with Express services (UPS, WC).
- 1–2 days for small orders
- 2–4 weeks for large selections
- 0.5–50 mg of dry powder sample in single glass vials, custom vials
- DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)