F873-0498 Screening compound: 1-(4-bromo-2-fluorophenyl)-3-{3-[2-(pyridin-4-yl)-3H-imidazo[4,5-b]pyridin-3-yl]propyl}urea

F873-0498 Screening compound: 1-(4-bromo-2-fluorophenyl)-3-{3-[2-(pyridin-4-yl)-3H-imidazo[4,5-b]pyridin-3-yl]propyl}urea
F873-0498 Screening compound: 1-(4-bromo-2-fluorophenyl)-3-{3-[2-(pyridin-4-yl)-3H-imidazo[4,5-b]pyridin-3-yl]propyl}urea alternative view

Chemical Structure Depiction of ChemDiv screening compound F873-0498
1-(4-bromo-2-fluorophenyl)-3-{3-[2-(pyridin-4-yl)-3H-imidazo[4,5-b]pyridin-3-yl]propyl}urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F873-0498

Molecular Formula

C21H18BrFN6O (C21 H18 BrFN6 O)

Compound Name

1-(4-bromo-2-fluorophenyl)-3-{3-[2-(pyridin-4-yl)-3H-imidazo[4,5-b]pyridin-3-yl]propyl}urea

IUPAC name

1-(4-bromo-2-fluorophenyl)-3-{3-[2-(pyridin-4-yl)-3H-imidazo[45-b]pyridin-3-yl]propyl}urea

SMILES

O=C(NCCCn1c(-c2ccncc2)nc2cccnc12)Nc(ccc(Br)c1)c1F

InChI

InChI=1S/C21H18BrFN6O/c22-15-4-5-17(16(23)13-15)28-21(30)26-9-2-12-29-19(14-6-10-24-11-7-14)27-18-3-1-8-25-20(18)29/h1,3-8,10-11,13H,2,9,12H2,(H2,26,28,30)

InChI Key

BARUOWIWDIUALT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14969698

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

469.32

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.566

Distribution Coefficient, logD

3.564

Water Solubility, LogSw

-3.64

Polar Surface Area

62.249

Acid Dissociation Constant (pKa)

10.13

Base Dissociation Constant (pKb)

4.78

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.30

F873-0498 in Drug Discovery

Included in Screening Libraries

Chelators targeting matrix metalloproteinases library (8930 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with F873-0498 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F873-0498?
Check Price and Availability of F873-0498, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F873-0498 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F873-0498
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F873-0498
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F873-0498 available by request