F891-1426 Screening compound: 1-(1-{[2-methyl-5-(5-methyl-1,2,4-oxadiazol-3-yl)thiophen-3-yl]sulfonyl}piperidine-4-carbonyl)-4-(pyridin-2-yl)piperazine

F891-1426 Screening compound: 1-(1-{[2-methyl-5-(5-methyl-1,2,4-oxadiazol-3-yl)thiophen-3-yl]sulfonyl}piperidine-4-carbonyl)-4-(pyridin-2-yl)piperazine
F891-1426 Screening compound: 1-(1-{[2-methyl-5-(5-methyl-1,2,4-oxadiazol-3-yl)thiophen-3-yl]sulfonyl}piperidine-4-carbonyl)-4-(pyridin-2-yl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound F891-1426
1-(1-{[2-methyl-5-(5-methyl-1,2,4-oxadiazol-3-yl)thiophen-3-yl]sulfonyl}piperidine-4-carbonyl)-4-(pyridin-2-yl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F891-1426

Molecular Formula

C23H28N6O4S2 (C23 H28 N6 O4 S2)

Compound Name

1-(1-{[2-methyl-5-(5-methyl-1,2,4-oxadiazol-3-yl)thiophen-3-yl]sulfonyl}piperidine-4-carbonyl)-4-(pyridin-2-yl)piperazine

IUPAC name

1-(1-{[2-methyl-5-(5-methyl-124-oxadiazol-3-yl)thiophen-3-yl]sulfonyl}piperidine-4-carbonyl)-4-(pyridin-2-yl)piperazine

SMILES

Cc(sc(-c1noc(C)n1)c1)c1S(N(CC1)CCC1C(N(CC1)CCN1c1ncccc1)=O)(=O)=O

InChI

InChI=1S/C23H28N6O4S2/c1-16-20(15-19(34-16)22-25-17(2)33-26-22)35(31,32)29-9-6-18(7-10-29)23(30)28-13-11-27(12-14-28)21-5-3-4-8-24-21/h3-5,8,15,18H,6-7,9-14H2,1-2H3

InChI Key

TVXCAYMLCOGMQT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27202036

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

516.65

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

3.095

Distribution Coefficient, logD

3.086

Water Solubility, LogSw

-3.22

Polar Surface Area

92.293

Acid Dissociation Constant (pKa)

23.63

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

47.80

F891-1426 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Epigenetics Focused Set (26518 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F891-1426 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F891-1426?
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What is the minimum amount of F891-1426 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F891-1426
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F891-1426
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F891-1426 available by request