F891-1577 Screening compound: 1-{[5-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-2-methylthiophen-3-yl]sulfonyl}-N-(2-methoxyphenyl)piperidine-4-carboxamide

F891-1577 Screening compound: 1-{[5-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-2-methylthiophen-3-yl]sulfonyl}-N-(2-methoxyphenyl)piperidine-4-carboxamide
F891-1577 Screening compound: 1-{[5-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-2-methylthiophen-3-yl]sulfonyl}-N-(2-methoxyphenyl)piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F891-1577
1-{[5-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-2-methylthiophen-3-yl]sulfonyl}-N-(2-methoxyphenyl)piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F891-1577

Molecular Formula

C23H26N4O5S2 (C23 H26 N4 O5 S2)

Compound Name

1-{[5-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-2-methylthiophen-3-yl]sulfonyl}-N-(2-methoxyphenyl)piperidine-4-carboxamide

IUPAC name

1-{[5-(5-cyclopropyl-124-oxadiazol-3-yl)-2-methylthiophen-3-yl]sulfonyl}-N-(2-methoxyphenyl)piperidine-4-carboxamide

SMILES

Cc(sc(-c1noc(C2CC2)n1)c1)c1S(N(CC1)CCC1C(Nc(cccc1)c1OC)=O)(=O)=O

InChI

InChI=1S/C23H26N4O5S2/c1-14-20(13-19(33-14)21-25-23(32-26-21)16-7-8-16)34(29,30)27-11-9-15(10-12-27)22(28)24-17-5-3-4-6-18(17)31-2/h3-6,13,15-16H,7-12H2,1-2H3,(H,24,28)

InChI Key

OIOQBVUEDVGEHS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27202099

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

502.62

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

4.354

Distribution Coefficient, logD

4.354

Water Solubility, LogSw

-4.24

Polar Surface Area

94.921

Acid Dissociation Constant (pKa)

10.63

Base Dissociation Constant (pKb)

2.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

43.50

F891-1577 in Drug Discovery

Included in Screening Libraries

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with F891-1577 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F891-1577?
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What is the minimum amount of F891-1577 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F891-1577
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F891-1577
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F891-1577 available by request